Amygdala unitary activity in the unrestrained cat

Sawa, Masaichi; dalgado, JoséM.R.

doi:10.1016/0013-4694(63)90115-9

Cited by 82 publications

(23 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study, oral sensory neurons that responded to several foods had significantly higher spontaneous activity than oral sensory plus vision neurons that responded only to some specific foods (2-tailed Student's t test, p < 0.01). Other physiological studies have reported neurons in the central and basolateral nuclei that responded to gustatory stimuli (Schwartzbaum and Morse, 1978;Yamamoto et al, 1981;Nishijo et al, 1986 Multimodal neurons Creutzfeldt et al, 1963;Sawa and Delgado, 1963). also reported that the multimodal responses were According to , inhibitory responses were abundant in the lateral nucleus, while in the present and other predominant in cat AM, while in the present and other studies, studies (Creutzfeldt et al, 1963), the multimodal responses were excitatory responses predominated (Machne and Segundo, 1956; rare in the lateral nucleus.…”

Section: Ingestion-related Neuronscontrasting

confidence: 41%

“…also reported that the multimodal responses were According to , inhibitory responses were abundant in the lateral nucleus, while in the present and other predominant in cat AM, while in the present and other studies, studies (Creutzfeldt et al, 1963), the multimodal responses were excitatory responses predominated (Machne and Segundo, 1956; rare in the lateral nucleus. reticular formation modulates sensory responses of the AM neurons (Sawa and Delgado, 1963) these discrepancies might be due to differences in experimental condition among these studies. In 3 cat studies, the animals were pharmacologically immobilized (Machne and Segundo, 1956;Creutzfeldt et al, 1963;, and in a fourth, the cat was freely behaving (Sawa and Delgado, 1963).…”

Section: Ingestion-related Neuronsmentioning

confidence: 88%

“…For auditory stimuli, various complex familiar and unfamiliar sounds such as clicks and those made when the experimenter intentionally rustled a cellophane bag while removing cookies to be placed on the turntable or by a wrench dropped on the floor, for example, were introduced besides familiar cue tones used in auditory discrimination task. Previous studies reported that the complex auditory stimuli were the most effective (Sawa and Delgado, 1963;O'Keefe and Bouma, 1969;Jacobs and McGinty, 1972). Intensities of the controlled complex sounds made by the experimenters ranged from 75 to 90 dB.…”

Section: Methodsmentioning

confidence: 99%

“…These studies suggest that these 2 types of neurons might respond preferentially to single or multiple sensory modalities, respectively. Previous electrophysiological studies reported preferential responses to visual stimulation in the lateral part of the AM in cat (Sawa and Delgado, 1963) and in monkey (Nakano et al, 1987) or in the anterolateral part ofthe AM in monkey (Sanghera et al, 1979;Ono et al, 1983). Multimodal responses have been reported in the basolateral nuclei in cat (Machne and Segundo, 1956; and the central nucleus in rabbit (Kapp et al, 1979).…”

mentioning

confidence: 98%

“…In cat AM it was reported that Amygdalar Modality-Specific Responses (Sawa and Delgado, 1963;O'Keefe and Bouma, 1969), but some of these responses habituated in repeated trials (Sawa and Delgado, 1963;Ben-At-i and La Salle, 1974). The latter results are consistent with our present results.…”

Section: Location Of Each Neuron Typementioning

confidence: 99%

See 4 more Smart Citations

Topographic distribution of modality-specific amygdalar neurons in alert monkey

1988

View full text Add to dashboard Cite

Neuronal activity in the amygdala (AM) was recorded from alert monkeys during performance of tasks that led to presentation of rewarding or aversive stimuli. The tasks had 3 phases: (1) discrimination (visual, auditory), (2) operant response (bar pressing), and (3) ingestion (reward) or avoidance (aversion). Neuronal activity was analyzed and compared during each of these phases. Of 585 AM neurons tested, 312 (53.3%) responded to at least one stimulus in one or more of 5 major groups: vision related, audition related, ingestion related, multimodal, and selective. Forty neurons (6.8%) in the anterior dorsolateral capsule of the basolateral nuclei responded exclusively to visual stimuli (vision related). Twenty-six neurons (4.4%) further posterior in the basolateral group responded only to auditory stimuli (audition related). During ingestion an additional 41 neurons (7.0%) increased their activity (ingestion related). These were in the corticomedial group and at the boundaries between the nuclei of the basolateral group. Of these, 27 responded only in the ingestion phase, 11 during ingestion and at the sight of food, and 3 during ingestion and to certain sounds. Throughout the AM other neurons (n = 117, 20.0%) responded to visual, auditory, and somesthetic stimuli and, when tested, to involuntary ingestion of liquid (multimodal). Of these, 40 responded transiently (phasic; 36 excited, 4 inhibited). The remaining 77 maintained their altered activity into the subsequent phases of the task (tonic; 69 excited, 8 inhibited). In each of these 4 categories, most cells were activated primarily by novel or unfamiliar stimuli, and their responses habituated during repeated stimulation. A small number of cells in the basolateral and the basomedial nuclei (n = 14, 2.4%) were highly selective in that they responded specifically to one biologically significant object or sound more than to any other stimuli (selective). Some of these neurons responded to both sight and ingestion of a specific food. In summary, most AM neurons responded vigorously to novel stimuli, and some of the neurons had multimodal responsiveness. These results suggest the AM is related to processing of new environmental stimuli and to those cross-modal association.

show abstract

Section: Ingestion-related Neuronscontrasting

confidence: 41%

Section: Ingestion-related Neuronsmentioning

confidence: 88%

Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 98%

Section: Location Of Each Neuron Typementioning

confidence: 99%

See 3 more Smart Citations

Topographic distribution of modality-specific amygdalar neurons in alert monkey

1988

View full text Add to dashboard Cite

show abstract

Projections from the orbital gyrus in the cat. II. To telencephalic and diencephalic structures

Mizuno

Clemente

Sauerland

1969

J of Comparative Neurology

View full text Add to dashboard Cite

Direct projections from the anterior part of the orbital gyrus and its immediate vicinity to telencephalic and diencephalic structures in the cat were investigated by means of the Nauta and Marchi methods.Association fibers were observed to project to the ipsilateral coronal gyrus, the anterior part of the insular cortex, and the lateral part of the pericruciate gyrus. Degenerated fibers originating at the site of the lesion were traced to the callosal body, and from there chiefly to the contralateral putamen and the contralateral orbital and coronal gyri. Projection fibers to the telencephalic nuclei were found to terminate in the head of the caudate nucleus, the putamen, claustrum, and anterior amygdaloid area. Degenerated fibers in the external capsule were traced to the prepyriform area and the lateral part of the olfactory tubercle. Some of these components were observed to join the medial forebrain bundle and could be followed to the lateral preoptic area. Orbitothalamic fibers were traced through the anterior limb of the internal capsule and the internal medullary lamina. These fibers were found to terminate in the rostroventral part of the nucleus reticularis and ventralis anterior, and in the rostra1 parts of the intralaminal nuclei.

show abstract

Projections from the amygdaloid complex to the cerebral cortex and thalamus in the rat and cat

Krettek

Price

1977

J of Comparative Neurology

736

308

View full text Add to dashboard Cite

Projections are described from the basolateral, lateral and anterior cortical nuclei of the amygdaloid complex, and from the prepiriform cortex, to several discrete areas of the cerebral cortex in the rat and cat and to the mediodorsal thalamic nucleus in the rat. These projections are very well-defined in their origin, and in their area of laminar pattern of termination. The basolateral amygdaloid nucleus can be divided into anterior and posterior divisions, based on cytoarchitectonic and connectional distinctions. In both the rat and cat the posterior division projects to the prelimbic area (area 32) and the infralimbic area (area 25) on the medical surface of the hemisphere. The anterior division projects more lightly to these areas, but also sends fibers to the dorsal and posterior agranular insular areas and the perirhinal area on the lateral surface. Furthermore, in the cat the perirhinal area is divided into two areas (areas 35 and 36) and the anterior division projects to both of these and also to a ventral part of the granular insular area; this last area is adjacent to, but separate from the auditory insular area and the second cortical taste area. In most of these areas, the fibers from the basolateral nucleus terminate predominantly in two bands: one in the deep part of layer I and layer II, and a heavier band in layer V (in the rat) or layers V and VI (in the cat). The lateral amygdaloid nucleus projects heavily to the perirhinal area, and also to the posterior agranular insular area. These fibers terminate predominantly in the middle layers of the cortex, although the cellular lamination in these two areas is relatively indistinct. The anterior cortical amygdaloid nucleus and the prepiriform cortex both project to the infralimbic area and the ventral agranular insular area, and the anterior cortical nucleus also projects to the posterior agranular area and the perirhinal area. In all of these areas, the fibers from these olfactory-related structures terminate in the middle of layer I. In the rat, the two divisions of the basolateral nucleus also project to the medial segment of the mediodorsal thalamic nucleus, with the anterior division projecting mainly to the posterior part of this segment and the posterior division to the anterior part. The endopiriform nucleus, deep to the prepiriform cortex, projects to the central segment of the mediodorsal nucleus; this may constitute the major olfactory input into the mediodorsal nucleus, since little or no projection could be demonstrated from the prepiriform cortex itself. Projections to the mediodorsal nucleus have not been found in the cat.

show abstract

Amygdala unitary activity in the unrestrained cat

Cited by 82 publications

References 15 publications

Topographic distribution of modality-specific amygdalar neurons in alert monkey

Topographic distribution of modality-specific amygdalar neurons in alert monkey

Projections from the orbital gyrus in the cat. II. To telencephalic and diencephalic structures

Projections from the amygdaloid complex to the cerebral cortex and thalamus in the rat and cat

Contact Info

Product

Resources

About