Amylin-like immunoreactivity in pancreatic X cells of the black-spotted frog Rana (Pelophylax) nigromaculata

Suzuki, Hirohumi; Yamamoto, Toshiharu

doi:10.1016/j.tice.2014.10.004

Cited by 5 publications

(2 citation statements)

References 33 publications

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“…Immunostaining was performed according to the methods described previously [ 18 ]. Briefly, the sections were washed overnight in 0.1 M PB (pH 7.4) containing 0.9% saline (PBS), and incubated with rabbit anti-human CXCL14 antibody (No.…”

Section: Methodsmentioning

confidence: 99%

CXCL14-Like Immunoreactivity Exists in Somatostatin-Containing Cells of Mouse Pancreas

Suzuki

Yamamoto

2015

Acta Histochem. Cytochem

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Immunohistochemical techniques were employed to investigate the distribution of the chemokine CXCL14, in the mouse pancreas. CXCL14-immunoreactive cells were detected in the peripheral region of the pancreatic islets and were immunoreactive for somatostatin, but not for glucagon, insulin, and pancreatic polypeptide. Immunoelectron microscopy indicated that the CXCL14-like peptide and somatostatin co-existed in the secretory granules. CXCL14, secreted from somatostatin-containing cells, may modulate insulin secretion in a paracrine fashion, and play a novel role in glucose homeostasis in addition to its well-known chemotactic activities.

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Section: Methodsmentioning

confidence: 99%

CXCL14-Like Immunoreactivity Exists in Somatostatin-Containing Cells of Mouse Pancreas

Suzuki

Yamamoto

2015

Acta Histochem. Cytochem

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“…In fact, amylin‐immunoreactive cells in the teleost pancreas correspond to B cells (Westermark et al., 2002). In the amphibian pancreas, amylin‐like immunoreactivity localizes in the X cells (Suzuki & Yamamoto, 2014) that were endocrinologically unidentified cells (Etayo et al., 2000), whereas in the reptile pancreas, amylin‐immunoreactive cells correspond to B and PP cells (Suzuki & Yamamoto, 2018). However, no studies have focused yet on amylin distribution and the co‐existing endocrine cell types in the avian pancreas despite the detected amylin mRNA (Fan et al., 1994).…”

Section: Introductionmentioning

confidence: 99%

Amylin‐like immunoreactivity in the extra‐islet peptide YY‐producing and glucagon‐immunoreactive cells in Japanese quail pancreas

Yanagida,

Yamamoto,

Suzuki

2024

Anat Histol Embryol

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In this study, we investigated amylin‐like substance distribution in the pancreas of Japanese quail (Coturnix japonica) using a specific anti‐rat amylin serum. We detected amylin‐immunoreactive cells dispersed in the pancreatic extra‐islet region but not in the islet region. The synthetic rat amylin‐containing serum pre‐absorption abolished the staining profile. Almost all amylin‐immunoreactive cells were immuno‐positive for peptide YY (PYY). In addition, certain amylin‐immunoreactive cells stained immuno‐positive for glucagon. Amylin and PYY co‐secreted from the extra‐islet cells might participate in the insulin and glucagon release regulation in the pancreas and food intake modulation through the central nervous system.

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Localization of amylin-like immunoreactivity in melanocyte-stimulating hormone-containing cells of the pars intermedia but not those of the pars distalis in the axolotl (Ambystoma mexicanum) pituitary

Suzuki

Yamamoto

2016

Acta Histochemica

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Amylin-like immunoreactivity in pancreatic X cells of the black-spotted frog Rana (Pelophylax) nigromaculata

Cited by 5 publications

References 33 publications

CXCL14-Like Immunoreactivity Exists in Somatostatin-Containing Cells of Mouse Pancreas

CXCL14-Like Immunoreactivity Exists in Somatostatin-Containing Cells of Mouse Pancreas

Amylin‐like immunoreactivity in the extra‐islet peptide YY‐producing and glucagon‐immunoreactive cells in Japanese quail pancreas

Localization of amylin-like immunoreactivity in melanocyte-stimulating hormone-containing cells of the pars intermedia but not those of the pars distalis in the axolotl (Ambystoma mexicanum) pituitary

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