“…In a previously reported case of amyloid goiter which was complicated by fatty infiltration, the thyroid US showed a high echogenicity [11]. In turn, Fontan et al [12] reported several cases of amyloid goiter in which cystic and solid lesions coexisted, which, on a morphological basis, can be reasonably diagnosed as adenomatous goiter similar to our case. In our patient, the existence of amyloid A protein in the thyroid was confirmed, and there were no neoplasms or other inflammatory diseases other than Crohn's disease.…”
“…In a previously reported case of amyloid goiter which was complicated by fatty infiltration, the thyroid US showed a high echogenicity [11]. In turn, Fontan et al [12] reported several cases of amyloid goiter in which cystic and solid lesions coexisted, which, on a morphological basis, can be reasonably diagnosed as adenomatous goiter similar to our case. In our patient, the existence of amyloid A protein in the thyroid was confirmed, and there were no neoplasms or other inflammatory diseases other than Crohn's disease.…”
“…A fine needle aspiration was positive for amyloid [66]. Two cases of amyloid goitre were reported by Fontan et al [67]. In the CT scan an enlarged thyroid mass with cystic components, showing solid parts of the goitre with high attenuation and moderate hypointensity on T 1 -and T 2 -weighted images in MRI could be detected.…”
Typical sonographic signs of amyloidosis could be found in the heart, bowel wall, liver, spleen, gallbladder and thyroid and were illustrated as pictorial assays.
“…A spectrum of cystic change has been described, including liquid-liquid levels and solid material floating within some of the cysts. 11 Appearances can extend to conglomerate cystic lesions separated by echogenic septa. 7, 11…”
Section: Discussionmentioning
confidence: 99%
“…Fontan et al . 11 reported several cases of amyloid goiter in which cystic and solid lesions coexisted, which on a morphological basis can be reasonably diagnosed as an adenomatous goiter.…”
Section: Discussionmentioning
confidence: 99%
“…10 The cysts, though lobular, were simple in appearance without the internal components as reported by Fontan et al . 11…”
Clinically symptomatic amyloid goiter is extremely rare. We report the case of a 76-year-old male patient under the care of the nephrologists with end stage renal failure of unknown aetiology. Concurrent investigation for a dysphagia causing goiter allowed primary diagnosis of amyloid by targeted fine needle aspiration (FNA) under ultrasound guidance. The imaging features are reviewed across multimodalities. This report highlights the usefulness of FNA in establishing diagnosis and the importance of maintaining clinical suspicion in patients with a concomitant history of a chronic inflammatory process.
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