An A-Type Proanthocyanidin from Prunus armeniaca

Prasad, D.; Joshi, Rakesh Kumar; Pant, G.; Rawat, Mahiraj Singh; Inoue, Ken‐ichiro; Shingu, Tetsuro; He, Zhaojun

doi:10.1021/np970383n

Cited by 14 publications

(9 citation statements)

References 8 publications

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“…A new A-type proanthocyanidin was isolated from the roots of P. armeniaca and its structure was assigned as ent-epiafzelechin-3-O-phydroxybenzoate-(4α → 8, 2α → O → 7)-epiafzelechin (Prasad et al, 1998). Later on, structures of three isomeric A-type proanthocyanidins isolated from the roots of P. armeniaca were elucidated as entepiafzelechin-(4α → 8, 2α → O → 7)-epiafzelechin (mahuannin A), ent-epiafzelechin-(4α → 8, 2α → O → 7)-(+)-afzelechin, and entepiafzelechin-(4α → 8, 2α → O→)-(−)-afzelechin (Rawat, Prasad, Joshi, & Pant, 1999).…”

Section: Polyphenolsmentioning

confidence: 99%

Insights into research on phytochemistry and biological activities of Prunus armeniaca L. (apricot)

Erdogan-Orhan

Kartal

2011

Food Research International

116

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Section: Polyphenolsmentioning

confidence: 99%

Insights into research on phytochemistry and biological activities of Prunus armeniaca L. (apricot)

Erdogan-Orhan

Kartal

2011

Food Research International

116

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“…The plant is a rich source of carbohydrates (both mono and polysaccharides) , polyphenols (Socher et al, 2010;Turans et al, 2007), carotenoids (ß carotene) (Ruiz et al, 2005), vitamins C and K, thiamine, niacin, iron, organic acids, phenols and volatile compounds, benzaldehyde, esters, norisoprenoids and terpenoids (Prasad et al, 1998;Mandal et al, 2007).…”

Section: Chemical Compositionmentioning

confidence: 99%

Effects of Apricot and Apricot Kernels on Human Health and Nutrition: A Review of Recent Human Research

Jaafar¹

2021

biochemmed

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Plants are one of the most important sources of medicine for humans to face diseases and disorders. Despite some advances in the field of allopathic system of medicine, adverse reactions have not been prevented from being an integral part of modern medicine. Plants are one of the important sources of drug discovery in both modern and traditional medicine systems worldwide. Recent developments in food and nutrition, consumer preferences shifted to foods rich in nutraceuticals. Furthermore 70% of marketed drugs are either natural or semisynthetic materials which derived from plants. Most literature on complementary alternative medicine worldwide either reports the nature of phytocomponents in medicinal plants or shows a mechanistic basis for their pharmacological activities. The medicinal and therapeutic effect of apricot has not been studied so far. In this review, an attempt has been made highlight the importance of apricot and its kernel in human health and nutrition by summarizing the literature reports published to date. Apricot exhibited diversified effects on degenerative diseases such as cancer, cardiovascular and hemostasis, at the same time has many pharmacological effects such as anti-parasitic, anti-aging, anti-atherosclerosis, renoprotective, hepatoprotective and antioxidant have been reported.

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“…Organic acids, phenols, volatile compounds, esters, terpenoids have also been isolated 11 . Prunus armeniaca kernels contain a substantial amount of dietary protein 12 along with significant amounts of oil and fiber 13 . In a previous study, 14 reported that sweet Prunus armeniaca kernels contain more oil than bitter kernels and that oleic acid and linoleic acid correspond to approximately 92 g/100 g of the total fatty acids present.…”

mentioning

confidence: 99%

Untitled

2021

IJPSR

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Excessive drug therapy, environmental pollutants, hepatic cancer and alcoholic intoxicants are the main causes of liver disorders. The hepatic disorders/toxicity can occur by several mechanisms like cytochrome P450 activation, lipid peroxidation, induction of nitric acid synthase, mitochondrial dysfunction, activation of pro-inflammatory mediators and bile acid-induced liver cell death. In spite of consistent human effort and drug discovery, the modern drug has very little to offer. (Prunus armeniaca) is commonly known as Khubani or moon of the faithful or Egg of the sun, which is used as folk medicine in traditional Indian medicinal system as well as worldwide medicinal system, belongs to the family Rosaceae. Prunus armeniaca fruit is the rich source of vitamin, carbohydrate, thiamine, niacin, iron, organic acids, phenols and volatile compounds viz. benzaldehyde, esters, norisoprenoids, terpenoids and minerals. The seed of Prunus armeniaca contain very small amount toxic hydrogen cyanide amygdalin, present in bitter prunus armeniaca kernels which are prescribed as anticancer drug, in asthma, cough and constipation. Prunus armeniaca is having some reported activities like anticancer, antiinflammatory, anti-tubercular properties and antimicrobial properties. Children consume Prunus armeniaca in form of candy and sauces. This review is an attempt to summarize the phytoconstituents, pharmacological action, drug interactions encountered and safety profile with use of Prunus armeniaca as a preventive and therapeutic aid to various ailments including hepatic and dental disorders. INTRODUCTION:Liver diseases are still a global health problem may be classified as acute or chronic hepatitis (inflammatory liver diseases), hepatosis (non inflammatory diseases) and cirrhosis (degenerative disorder resulting in liver fibrosis). According to WHO (1993) 1 , about 80% of the world population rely on the use of traditional medicine which is predominantly based on plant materials. Unfortunately, treatments of choice for liver diseases are controversial because conventional or synthetic drugs for the treatment of these diseases are insufficient and sometimes cause serious side effects 2 .

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An A-Type Proanthocyanidin from Prunus armeniaca

Abstract: Roots of Prunus armeniaca yielded a new A-type proanthocyanidin whose structure was assigned as ent-epiafzelechin-3-O-p-hydroxybenzoate-(4alpha-->8, 2alpha-->O-->7)-epiafzelechin (1). The structure of 1 was determined through extensive 1D and 2D NMR studies.

Cited by 14 publications

References 8 publications

Insights into research on phytochemistry and biological activities of Prunus armeniaca L. (apricot)

Insights into research on phytochemistry and biological activities of Prunus armeniaca L. (apricot)

Effects of Apricot and Apricot Kernels on Human Health and Nutrition: A Review of Recent Human Research

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