An ABO-blood group abnormality leading to the detection of a colon-carcinoma

Northoff, Hinnak; Wölpl, A; Bewersdorf, H.; Faulhaber, J.-D.

doi:10.1007/bf00320275

Cited by 4 publications

(2 citation statements)

References 8 publications

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“…Acquired B antigen has been thought to be asso ciated with neoplasms of the large bowel, and it has been suggested that following its detection a search should be made for such a lesion [Northoff et al, 1983]. Careful histological assessment of this patient's operative sample failed to reveal malignancy.…”

Section: Discussionmentioning

confidence: 99%

Transient Acquired Blood Group B Antigen Associated with Diverticular Bowel Disease

Roath¹,

Todd²,

Shaw³

1987

Acta Haematol

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Transient acquired B red cell antigen was found in a patient with inflammatory bowel disease. Removal of the affected portion of the bowel was associated with disappearance of the B antigen. This phenomenon has usually been recorded in association with neoplasms of the bowel, but appears to be a marker for the release of bacterial enzymes into the systemic circulation associated with breakdown of the normal bowel barrier to such materials.

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Section: Discussionmentioning

confidence: 99%

Transient Acquired Blood Group B Antigen Associated with Diverticular Bowel Disease

Roath¹,

Todd²,

Shaw³

1987

Acta Haematol

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“…Immunological and biochemical analysis of whole mixed saliva is useful in the diagnosis of various systemic diseases such as Gougerot-Sjogren syndrome (Pennec et al 1982), colon carcinoma (Northoff et al 1983), and fucosidosis (Den Tandt & Jaeken 1979), as well as in studies of human genetics (Teng & Tan 1979, Herron et al 1980, Roberts et al 1981. One important component in these anaiyses are salivary enzymes.…”

Section: Introductionmentioning

confidence: 99%

Effect of periodontal therapy on salivary enzymatic activity

Zambon

Nakamura

Slots

1985

J of Periodontal Research

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This study determined changes in the levels of enzymes in whole mixed saliva of adults following periodontal therapy including two or more sessions of meticulous periodontal scaling and root planing and 1 g/day of tetracycline‐HCI for 14 days. Clinical variables assessed at baseline and 2 weeks after treatment included Gingival Index, Plaque Index, periodontal pocket depth, and gingival crevicular fluid flow. Subgingival specimens obtained from the deepest periodontal pocket in each quadrant were analyzed for Bacteroides gingivalis and Bacteroides intermedius using indirect immunofluorescence microscopy and for bacterial morphotypes using bright light phase contrast microscopy. The enzymatic profile of unstimulated whole mixed saliva was determined using the API ZYM and API ZYM AP micromethod systems. Periodontal treatment significantly reduced gingival inflammation and the proportions of subgingival black‐pigmented bacteroides and motile organisms. However, the Plaque Index and total salivary bacterial counts remained virtually unchanged. Treatment also resulted in reduced salivary levels of caprylate esteraselipase, leucine, valine, and cystine aminopeptidases, trypsin, β‐galactosidase, β‐glucuronidase, and β‐glucosidase. The present study indicates that the efficacy of periodontal treatment may be readily monitored by changes in levels of activity of specific enzymes in whole saliva.

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