“…It was for three decades the active device of choice in the analog design of integrated circuits used in wide applicability in electronics, including computers, televisions, mobile phones, audio amplifiers, industrial control, and radio-frequency (RF) circuits of the wireless systems [1], but today the use of the BJT has declined in favor of the CMOS technology in the design of digital integrated circuits (ICs) [2][3][4]. Due to the low impedance at the base, high transconductance, and output resistance compared to MOS devices, the BJT is characterized as currentcontrolled current source useful to compute nonlinear functions by their logarithm dependence between base-emitter voltage , collector current , and temperature, which recently has led to its integration into the CMOS-based architectures [5][6][7][8]. Currently, the BJT has been shown to be a viable option as transducer in electrochemical sensor, because it has significantly greater sensitivity and signal to noise ratio (SNR) and minor calibration requirements independent of voltages for operation, which implies that optimal measurements can be made over the entire sensing range, for example, to detect both [Cl − ] ions and biomolecules in portable diagnostics [9,10].…”