An Adverse Reaction in the Pediatric Sleep Laboratory

Reppucci, Diana; Medin, Debra; Al-Saleh, Suhail; Smith, Mary Jane; Barter, Jill; Amin, Reshma

doi:10.1155/2016/9712579

Cited by 6 publications

(2 citation statements)

References 3 publications

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“…Isopropyl alcohol was a culprit in swabs following neurosurgery [66], and iodine contact allergy has even been associated with the use of a continuous positive airway pressure (CPAP) [67]. Neomycin and particularly bacitracin are important antibiotic allergens in the USA [6], whereas nitrofurazone is still a frequent sensitizer in Turkey, antibiotics being omitted in most European countries because of their high sensitizing potential [68].…”

Section: Topical Pharmaceutical Productsmentioning

confidence: 99%

Contact Allergy in Children

Goossens

Morren

2020

Contact Dermatitis

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Contact allergy in children is more frequent than previously suspected. Metals, ingredients of pharmaceutical and cosmetic products, preservatives/biocides, para-phenylenediamine, rubber additives, plastics and resins, and plants are known sensitizers in them. In adolescents, occupation-induced allergens may be involved as well. Sometimes unusual clinical presentations of allergic contact dermatitis can be observed. If there is a suspicion by history and clinical picture, or there is an unexplained eczema at particular body sites, patch testing should be performed at all ages. Patch testing in children is safe, but false-positive (as false-negative) reactions are, of course, possible. Patch test reactions must be interpreted carefully, particularly in atopic subjects, since their skin is readily irritated; this is especially the case for metals. An abbreviated baseline series, supplemented with relevant allergens from other test series, as well as contacted products and respective ingredients suggested by the history, should be patch tested.

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Section: Topical Pharmaceutical Productsmentioning

confidence: 99%

Contact Allergy in Children

Goossens

Morren

2020

Contact Dermatitis

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“…32,48,50 Sleep disorders were reported in three out of the 34 case reports reviewed, including sleep-disordered breathing (1), OSA (1), and skin dermatitis due to CPAP mask (1). 34,53,54…”

Section: Sleep Disordersmentioning

confidence: 99%

Cornelia de lange manifestations in otolaryngology: A systematic review and meta‐analysis

2019

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Objectives Cornelia de Lange syndrome (CdLS) is a rare genetic disorder. Our goal was to systematically review the literature regarding otolaryngology manifestations of CdLS. Methods We systematically reviewed the PubMed, Embase, CINAHL, Scopus, and Google Scholar databases for original articles of otolaryngology manifestations for patients with CdLS. These articles were analyzed, and pooled prevalence was calculated. Results We analyzed 1,310 patients included in 35 case series and 34 case reports. Hearing loss was present for many patients (27 studies), with sensorineural hearing loss affecting 40.3% (95% confidence interval [CI]: 17.3–63.4) and conductive affecting 22.7% (95% CI: 5.7–39.7). Recurrent acute otitis media was the most frequent infectious manifestation, with 56.5% (95% CI: 34.1–78.4) in seven studies, followed by recurrent airway infections with 44.1% (95% CI: 11.0–87.1) in five studies. Forty‐nine (49.7%) percent of patients (95% CI: 25.9–73.6) in nine studies had dysphagia, and 76.6% (95% CI: 59.8–93.3) in four studies had some degree of dysphonia. Craniofacial anomalies were reported in 30 studies, with micrognathia (53.1%; 95% CI: 34.1–72.1) and high arched palate (70.6%; 95% CI: 56.5–84.8) commonly reported. Additional physical exam abnormalities reported included those involving: lips (76.8%; 95% CI: 65.3–88.4), dentition (65.1%; 95% CI: 27.2–100), mouth (85.5%; 95% CI: 76.2–93.8), and eyelashes (87.1%; 95% CI: 77.2–96.9). Sleep‐disordered breathing or obstructive sleep apnea affected 25.8% (95% CI: 11.4–40.2) of patients (7 studies). Airway anomalies were reported in 11 case reports. Conclusion This is the first comprehensive evaluation of otolaryngologic manifestations in the CdLS literature. Most reported hearing loss and craniofacial anomalies. Sleep disorders occurred in a minority of patients, whereas airway disorders were primarily reported in case reports. These conditions should be further examined given their potential life‐threatening implications. Level of Evidence 3a Laryngoscope, 130:E122–E133, 2020

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Contact Allergy in Children

Goossens¹,

Morren²

2019

Contact Dermatitis

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An Adverse Reaction in the Pediatric Sleep Laboratory

Cited by 6 publications

References 3 publications

Contact Allergy in Children

Contact Allergy in Children

Cornelia de lange manifestations in otolaryngology: A systematic review and meta‐analysis

Contact Allergy in Children

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