An aggressive form of<i>Haemophilus parainfluenzae</i>infective endocarditis presenting with limb weakness

McCann, Naina; Barakat, Mohamad Fahed; Schafer, Frank

doi:10.1136/bcr-2017-223775

Cited by 5 publications

(2 citation statements)

References 11 publications

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“… 4 The course of HACEK IE is classically considered insidious. However, this case mirrors other reports 5 6 of H. parainfluenzae acting aggressively in previously healthy people.…”

Section: Discussionsupporting

confidence: 90%

Haemophilus parainfluenzaeendocarditis presenting with symptoms of COVID-19

Finch¹,

Gerdzhikov²,

Buttery

2021

BMJ Case Rep

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A young man presented early in the UK’s second COVID-19 pandemic surge with a twelve-day history of fever, dry cough, breathlessness, myalgia and loss of smell and taste. His chest X-ray showed bilateral ground-glass opacities. He was treated for COVID-19 pneumonitis but covered for bacterial infection with antibiotics. He developed shock and respiratory failure, requiring vasopressors and continuous positive airway pressure. He improved but experienced transient visual disturbances and headache. Nasopharyngeal swabs and antibody tests for COVID-19 were negative. Blood cultures grew Haemophilus parainfluenzae. A new murmur prompted an echocardiogram. This confirmed a large, mobile mitral valve vegetation. An MRI of the brain showed bilateral embolic infarcts. He underwent urgent mitral valve repair and made an excellent recovery. Whether COVID-19 caused his presenting symptoms or facilitated the bacteraemia remains unclear. It seems more likely that infective endocarditis masqueraded as COVID-19. Clinicians should be aware of how context of the pandemic can bias diagnostic reasoning.

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“… 4 The course of HACEK IE is classically considered insidious. However, this case mirrors other reports 5 6 of H. parainfluenzae acting aggressively in previously healthy people.…”

Section: Discussionsupporting

confidence: 90%

Haemophilus parainfluenzaeendocarditis presenting with symptoms of COVID-19

Finch¹,

Gerdzhikov²,

Buttery

2021

BMJ Case Rep

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show abstract

“…In contrast, Haemophilus parain uenzae may colonize the human upper respiratory tract and is usually considered to be a member of the normal oral micro ora [5][6][7]. It is less pathogenic but does cause occasional cases of bacterial endocarditis [8,9], sepsis [10], urethritis, upper respiratory tract infections, intracerebral abscess [11], etc.…”

Section: Introductionmentioning

confidence: 99%

Influencing factors in the satellitism test of Haemophilus influenzae and Haemophilus parainfluenzae supplemented V factor by Staphylococcus aureus

Wang²,

Wang

et al. 2020

Preprint

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Background: Many factors affecting satellitism test are not clear, and it is difficult to avoid misidentified even if the medium is properly selected. We investigated the factors that cause false positives of Haemophilus influenzae and false negatives of Haemophilus parainfluenzae in the satellitism test supplemented V factor by Staphylococcus aureus.Methods: H. influenzae (four reference strains and 47 clinical isolates), H. parainfluenzae (two reference strains and 67 clinical isolates), four different media, and two strains of S. aureus activated on two different media were involved in this study.Results: The type of medium used to activate S. aureus was the most common factor causing false positives of H. influenzae, followed by the strain of S. aureus, and again the type of medium used for the experiment. The production of false negatives of H. parainfluenzae was only related to the medium used in the experiment.Conclusions: Tryptic soy agar and S. aureus (ATCC 25923) activated with nutrient agar should be used in the satellitism test for Haemophilus spp. to improve the accuracy of the test.

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A study of various factors affecting satellitism tests of Haemophilus influenzae and Haemophilus parainfluenzae using Staphylococcus aureus as the source of NAD

Wang²,

Wang

et al. 2022

Journal of Microbiological Methods

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An aggressive form ofHaemophilus parainfluenzaeinfective endocarditis presenting with limb weakness

Cited by 5 publications

References 11 publications

Haemophilus parainfluenzaeendocarditis presenting with symptoms of COVID-19

Haemophilus parainfluenzaeendocarditis presenting with symptoms of COVID-19

Influencing factors in the satellitism test of Haemophilus influenzae and Haemophilus parainfluenzae supplemented V factor by Staphylococcus aureus

A study of various factors affecting satellitism tests of Haemophilus influenzae and Haemophilus parainfluenzae using Staphylococcus aureus as the source of NAD

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