An analysis of concentration of sucrose, endogenous pH, and alteration in the plaque pH on consumption of commonly used liquid pediatric medicines

Abstract

These sweeteners along with their low endogenic pH form a high cariogenic formulation. Thus, nonsucrose (noncariogenic) or sugar-free medications are needed to be prescribed along with proper oral hygiene care to the children under medication.

Cariogenic Potential of the commonly Prescribed Pediatric Liquid Medicaments in Kingdom of Saudi Arabia: An in vitro Study

“…The HANNA digital pH meter used in our study is more accurate and efficient than conventional electrode pH meter. 12,22 In our study, three out of seven PLM had pH below the critical pH (5.5) of the oral cavity. The range was from 4.22 to 6.10 showing that all were acidic.…”

“…In an in vivo study, it was concluded that PLM causes a drop in plaque pH sufficient to cause decalcification within 2 to 10 minutes, following its initial exposure to the teeth. 12 Furthermore, high concentrations of fermentable carbohydrates in PLM may facilitate the growth of Streptococcus mutans by rapidly metabolizing sugars to acids; thus, initiating enamel demineralization. The HANNA digital pH meter used in our study is more accurate and efficient than conventional electrode pH meter.…”

“…Various other studies have also confirmed that these preparations are cariogenic and acidogenic in nature. [10][11][12][13] Thus, this study was conducted to investigate the cariogenic potential of the commonly used PLMs in Jazan region, Kingdom of Saudi Arabia. The cariogenic potential of these medicaments depends on many factors, such as pH, titratable acidity, sugar content, viscosity, frequency of ingestion, and physical and chemical properties affecting adherence to the enamel surface.…”

“…10 Many of the authors have expressed their concerns that oral liquid medications contribute to the total sugar load and to the development of dental caries in children. [11][12][13] However, in the Middle Eastern countries (especially Kingdom of Saudi Arabia), there have been no studies reported about the cariogenic potential of the commonly prescribed PLM to children. Since the PLM are routinely dispensed at the various hospitals and primary health…”

Effects of the Enamel Erosion Caused by Certain Antipyretic and Analgesic Medicines for Children

“…In addition, Sunitha et al 14) said inappropriate use of liquid medicines would have enormous potential to induce dental caries as syrups such as antipyretic·analgesic medicines, cough syrup with 10% of sucrose made experimental plaque's pH lower.…”