Polymeric materials are increasingly used in the automotive industry, aeronautics, medical device industry, etc. due to their advantage of providing good mechanical strength at low weight. The incremental forming process for polymeric materials is gaining increasing importance because of the advantages it offers: relatively complex parts can be produced at minimum cost without the need for complex and expensive dies. Knowing the main strains and especially the thickness reduction is particularly important as it directly contributes to the mechanical strength of the processed parts, including in operation. For the design of experiments, the Taguchi method was chosen, with an L18 orthogonal array obtained by varying the material on two levels (polyamide and polyethylene) and the other three parameters on three levels: punch diameter (6 mm, 8 mm and 10 mm), wall angle (50°, 55° and 60°) and step down (0.5 mm, 0.75 mm and 1 mm). The output parameters were strain in the x direction, strain in the y direction, major strain, minor strain, shear angle and thickness reduction. Two analyses were conducted: signal-to-noise ratio analysis with the smaller-is-better condition and analysis of variance. The optimum values for which the thickness was reduced were the following: wall angle of 50°, punch diameter of 10 mm and step down of 0.75 mm.