An Antianemic Factor in Desiccated Stomach

Immunologic Studies With Intrinsic Factor in Man*

“…One week thereafter, 0.5 ml of P-HIFC without adjuvant was administered subcutaneously into the left upper arm. No immediate untoward effects were noted; however, patient J. W. reported mild itching at the injection site, beginning within 4 to 6 hours and per- 2 Difco Laboratories, Detroit, Mich. 3 Thimerosol, Eli Lilly and Co., Indianapolis, Ind. (13).…”

“…Two elderly males (J. W. and J. D.) with treated pernicious anemia, previously diagnosed on the basis of 1) macrocytic anemia with megaloblastic bone marrow, 2) gastric anacidity after maximal histamine stimulation, 3) low vitamin B,.! and normal folate serum levels, and 4) subnormal absorption of Co'-vitamin B,2 corrected by orally administered HIFC, were injected repeatedly with P-HIFC in the following manner: to a 100 mg per 100 ml concentration of P-HIFC in sterile saline was added sufficient 2% merthiolate 3 solution to result in a 1: 1,000 concentration. Aerobic and anaerobic cultures of this preparation were consistently sterile.…”

A classified bibliography on psychodietetics.

“…According to Sturgis, Isaacs and Riddle (102) as well as Baker, Bordley and Longcope (4), the use of liver in the treatment of this disease dates from the 1926 publication of Minot and Murphy (74,75,76,77). Other investigators have since found that desiccated hog's stomach is fully as efficacious as liver (13,24,25,97,103,104,119). Ungley (107) finds that whole brain is also effective.…”