An array configuration to increase the performance of a biosensor

A new approach for noninvasive transdermal determination of blood uric acid levels

“…Noninvasive transdermal determination of blood uric acid levels that reported for other sensors, 28,32,33 but slightly lower than that reported by Zhang et al (0.2-1 mM). 34 The sensitivity of UAB-1×1-ZnO 2 (3.369 μA/mM) in this study was lower than that reported by Luo et al (16.6 μA/mM), 32 but higher than those reported by Zhang et al (5.5 nA/mM) 34 and Ching et al (1.55 μA/mM).…”

“…Due to the usually low concentration of uric acid that can be extracted transdermally, biosensors for this purpose should ideally have high sensitivity. Many researchers have focused on the use of nanoparticles, 20,21 carbon nanotubes, 22,23 electrontransfer mediators, 24,25 bimetallic materials, 26,27 bienzymes, 22,23 and array configurations 28 to enhance the sensitivity of biosensors. To the best of our knowledge, there have been no reports of the use of a combination of the above approaches to enhance biosensor sensitivity.…”