An assessment of mumps vaccine effectiveness by dose during an outbreak in Canada

The association between the incidence of mumps and meteorological parameters in Taiwan

“…15,16 Using a Poisson regression analysis and a case-crossover methodology, we analyzed mumps data reported to the Taiwan CDC from 2006 to 2011. We found that the incidence of mumps was highest during the summer months but that incidence was positively correlated with increased mean temperature and vapor pressure in both the long-term and acute effect analyses.…”

Outbreak-related mumps vaccine effectiveness among a cohort of children and of young adults in Germany 2011

“…28 However, given a VE of 90% and a basic reproductive number of 4, 6, or 8, respectively, Deeks and colleagues estimated that coverage needs to exceed 83.3%, 92.6%, or 97.2% to provide herd immunity and prevent mumps outbreaks. 29 In contrast, in the adult cohort the number of received doses varied according to age, and only about a third had received 2 vaccinations. Coverage in the now adult age groups had historically been low in Germany and only increased in the recent decade: a cross-sectional study in 1988 examining ~86 100 VCs of 10-to 12-y-old children in Bavaria yielded a mumps vaccination coverage of only 55%.…”

“…Since previous surveys suggest that a substantial proportion of young adults living in the Western federal states of Germany has <2 mumps vaccinations, thereby forming a relevant pool of susceptibles for further outbreaks, it seems plausible that from a public health point of view priority should be given to close these vaccination gaps. Given the current mumps vaccine, two-dose coverage rates should exceed 95% 29 in all age groups born after vaccine introduction into the routine schedule to prevent future outbreaks. Therefore, in Germany interventions are needed that are specifically targeted at adolescents and young adults who have received <2 vaccine doses during their childhood or have an unknown vaccination status.…”

Epidemiology and the economic assessment of a mumps outbreak in a highly vaccinated population, Orange County, New York, 2009–2010

“…20 For a single dose the effectiveness is 78% (median, range: 49-92%) and for 2 doses it is 88% (median, range: 66-95%). 21,22 All the cases were village residents except for 3 case-patients who worked in the village. There was no secondary transmission to individuals who lived outside the village indicating that population immunity provided by high two-dose coverage levels of MMR vaccine may have been more effective in limiting transmission in a less crowded setting.…”