An assessment of rates of psychiatric morbidity and functioning in HIV disease

McDaniel, J. Stephen; Fowlie, Elisabeth; Summerville, Mary B.; Farber, Eugene W.; Cohen-Cole, Steven A.

doi:10.1016/0163-8343(95)00066-z

Cited by 73 publications

(41 citation statements)

References 24 publications

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“…The behavioral aspect of discontinuing the therapy because of feeling well initially could be effectively handled by the behavioral segment of CBT [21]. Several studies over the years have tried to assess the role of CBT in the treatment of HIV patients in various settings [22,23]. In a study of adherence to therapy in HIV-positive individuals, five distinct subgroups were identified, with variations noted over the course of the 4-week study.…”

Section: Discussionmentioning

confidence: 99%

Cognitive behavioral therapy improves adherence to antiretroviral therapy in HIV-infected patients: a prospective randomized controlled trial from eastern India

Chattopadhyay¹,

Ball²,

Kargupta³

et al. 2017

HIV & AIDS Review

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We know that human immunodeficiency virus (HIV) is an important pandemic of modern generation causing large death toll worldwide. India is also no exception with 2.12 million people already affected by HIV. The only way to reduce morbidity and mortality due to HIV is antiretroviral therapy (ART). But a high degree of adherence is critical for the effectiveness of ART, and non-adherence is associated with an overall poor outcome in HIV patients. We conducted a randomized controlled prospective study to find out the factors responsible for non-adherence to ART and to assess the role of cognitive behavioral therapy (CBT) to improve adherence. In this study, 60 HIV/AIDS patients with non-adherence (< 95% adherence) were randomized into two groups consisting of 30 patients each, one group (intervention) was administered structured CBT and the other group (control) was put on standard therapy. Factors responsible for non-adherence were overconcern about side effects (33%), polarized thinking (27%), mind reading (27%), and magnification (20%).

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Section: Discussionmentioning

confidence: 99%

Cognitive behavioral therapy improves adherence to antiretroviral therapy in HIV-infected patients: a prospective randomized controlled trial from eastern India

Chattopadhyay¹,

Ball²,

Kargupta³

et al. 2017

HIV & AIDS Review

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“…Além disso, o diagnóstico de depressão em indivíduos infectados pelo HIV pode ser dificultado devido: à tendência dos profissionais de saúde em considerar a depressão reação normal ao diagnóstico da infecção; à presença de sintomas somáticos que complicam o diagnóstico diferencial; ao receio de alguns pacientes em expressarem seus sentimentos e aos efeitos colaterais psiquiátricos de alguns anti-retrovirais (Penzak et al, 2000;Fulk et al, 2004;Chandra et al, 2005). Dois trabalhos avaliaram a prevalência de depressão em indivíduos HIV-positivos de ambos os sexos (Maj et al, 1994;McDaniel et al, 1995) (Tabela 1). O primeiro, de Maj et al (1994), foi um estudo multicêntrico e controlado que incluiu 955 indivíduos (602 HIV-positivos e 353 controles) de cinco países (Brasil, Tailândia, Zaire, Alemanha e Quênia).…”

Section: Prevalência De Depressão Em Indivíduos Infectados Pelo Hivunclassified

“…A diferença entre os grupos não foi significativa. O segundo, um estudo não-controlado, mostrou prevalência de depressão de 29% nos homens infectados pelo HIV e 35% nas mulheres soropositivas (McDaniel et al, 1995). Ambos os trabalhos, entretanto, incluíram indivíduos de populações variadas (heterossexuais, homossexuais e usuários de drogas, entre outros) e que se encontravam em diferentes estágios da infecção pelo vírus.…”

Section: Prevalência De Depressão Em Indivíduos Infectados Pelo Hivunclassified

Infecções virais e depressão

Stumpf¹,

Rocha

Proietti

2006

J. bras. psiquiatr.

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ResumoObjetivo: A associação entre depressão e viroses é estudada há quase dois séculos, com resultados conflitantes. O objetivo deste trabalho é fazer uma análise crítica dos estudos existentes na literatura sobre essa relação. Métodos: A pesquisa bibliográfica utilizou as fontes eletrônicas de busca MEDLINE e LILACS (1966 a agosto 2005). As referências dos artigos foram utilizadas como fonte adicional de consulta. Resultados: Foram abordados os trabalhos que trataram da associação entre depressão e os vírus HIV, HCV, EBV, influenza, HSV, HBV, HAV, BDV e HTLV. A relação entre HIV e depressão mostrou-se bem documentada na literatura. Existem indícios de que a prevalência desse transtorno nos indivíduos infectados pelo HIV seja maior que a encontrada nos soronegativos. Além disso, estudos constataram que a depressão está associada a pior prognóstico da infecção. Quanto à associação entre HCV e depressão, os trabalhos sugeriram maior prevalência desse transtorno psiquiátrico nos portadores do HCV comparados à população geral. Não existem evidências científicas suficientes para dar suporte à relação entre os demais vírus e depressão. Conclusão: As associações mais bem fundamentadas foram aquelas entre depressão e os vírus HIV e HCV. A relação entre as demais viroses e depressão precisa ser mais bem estudada, e trabalhos com delineamento adequado se fazem necessários. Palavras-chave: depressão, viroses, HIV, HCV, HTLV. AbstractObjective: The association between depression and viruses has been evaluated for almost two centuries now, with conflicting results. The objective of the present study is to perform a critical review of published studies in the literature about this relationship. Methods: Databases MEDLINE and LILACS were searched between 1966 and 2005 (until August). The references of the articles were used as additional source of data. Results: Studies about the link between depression and infection with viruses HIV, HCV, EBV, influenza, HSV, HBV, HAV, BDV and HTLV were analyzed. The association between HIV and depression was well documented in literature. There are evidences that the prevalence of this disorder in HIV-infected individuals is greater than that found in seronegatives. Moreover, studies concluded that depression is associated with a worse course of infection. Regarding the link between HCV and depression, studies suggested a greater prevalence of this psychiatric disorder in HCV-infected people compared with general population. There is not enough scientific evidence to support the association between other viruses and depression. Conclusion: The best-studied relationships were those between depression and viruses HIV and HCV. Regarding the association of other viruses with depression, more research is needed.

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“…Some studies report depression rates as high as 52% in people aging with HIV [10]. Among the wide spectrum of psychiatric comorbidities, depression seems to show the strongest association with adverse health outcomes in PLWH, such as non-adherence to antiretroviral therapy, increase of HIV-related morbidity, and greater overall mortality [11][12][13].…”

Section: Effects Of Age and Depression In Older Plwhmentioning

confidence: 99%

Home-Based Telepsychiatry and in-Home CBT for Management of Major Depression in HIV-Positive Adults 50 Years and Older: A Proof-of-Concept Study

Bourgeois¹

2017

Acta Psychopathol

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Background: HIV clinicians are increasingly confronting mild major depression and dysthymic disorder in their older patients. Despite rapid advances in technologybased interventions in the medical field, particularly in psychiatric treatment, the utilization of this resource in mental health services delivery research in the context of HIV disease has been limited. Home-based telemedicine (HBT) -which in this article mainly refers to telepsychiatry -combined with in-home cognitive behavioral therapy (CBT) may serve as a promising clinical strategy through which a broader patient population can be treated. Objective:The current study aimed to assess: (1) change in psychiatric symptoms, (2) change in perception towards the acceptability of telemedicine, and (3) the viability of using a combined treatment of in-home CBT and HBT.Methods: Subjects engaged in 6-12 weeks of weekly in-home CBT paired with monthly follow-up home-based telepsychiatry (HBT) sessions for the management of mild to moderate depression in older persons living with HIV (PLWH).Results: 3 subjects completed the current study. Subjects reported comfortability with receiving services by telemedicine, ability to talk freely, and perceived privacy of the sessions. Clinician feedback further supported the feasibility and acceptability of using this delivery of treatment. Conclusion:Data gathered from the current study support the findings from the predecessor study. HBT coupled with in-home CBT may serve as a feasible method for the management and treatment of mild to moderate depression in PLWH aged 50+ in an urban setting. Larger clinical trials focused on older PLWH using a similar treatment regimen will help provide more insight into viable healthcare models for this growing population.

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An assessment of rates of psychiatric morbidity and functioning in HIV disease

Cited by 73 publications

References 24 publications

Cognitive behavioral therapy improves adherence to antiretroviral therapy in HIV-infected patients: a prospective randomized controlled trial from eastern India

Cognitive behavioral therapy improves adherence to antiretroviral therapy in HIV-infected patients: a prospective randomized controlled trial from eastern India

Infecções virais e depressão

Home-Based Telepsychiatry and in-Home CBT for Management of Major Depression in HIV-Positive Adults 50 Years and Older: A Proof-of-Concept Study

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