An eco-benign and highly efficient procedure for N-acylation catalyzed by heteropolyanion-based ionic liquids using carboxylic acid under solvent-free conditions

Structural elucidation of thermolysis products of methyl N-methyl-N-nitrosoanthranilate

“…IR, 1 H and 13 C NMR spectroscopic data are in accordance with Han et al 31 Methyl N-benzoylanthranilate ( Table 3. 1 H and 13 C NMR spectroscopic data are in accordance with Chen et al 33 Although, we observed the presence of two rotamers in the NMR spectra, as it was previously published, 33 herein we give only the data for the major rotamer, as the fraction 3 was a complex mixture of several compounds. White amorphous solid; UV absorptions: λ max (CH 3 Table 3.…”

“…Although the presence of two rotamers was observed in our NMR spectra of 7, as previously reported, 33 herein we report only 1 H and 13 C NMR data for the major rotamer (Table 3) unambiguously identified in the complex mixture. NMR analysis of fraction 3 (without further purification) corroborated the identity of 7.…”

“…Having this in mind we assumed that the compound in question was methyl N-benzoylanthranilate (6) (Fig. 33 However, herein we give only the data for the major rotamer, as the fraction 3 was a complex mixture of several compounds. To confirm this tentative identification we synthesized the mentioned compound starting from benzoyl chloride and methyl anthranilate in the presence of Et 3 N following the procedure of Schneider et al 27 and the structure of the synthetized compound was confirmed by 1D and 2D NMR (Fig.…”

An Efficient, Eco-friendly and Sustainable One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones Directly from Alcohols Catalyzed by Heteropolyanion-Based Ionic Liquids

“…Based on our previous investigations into HPAILs catalyzed reactions [ 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 111 , 112 ], N -substituted imidazole, pyridine and triethylamine based HPAILs were chosen as potential catalysts for this tandem oxidative cyclocondensation ( Figure 1 ).…”

“…Recently, a large number of publications have clearly shown that the main benefit of microwave (MW) chemical processing is the significant rate enhancements, yield and selectivity improvements as well as less environmental pollution, matching with the goals of green chemistry [ 100 , 101 , 102 ]. Following our continued investigation into the development of useful and sustainable synthetic methodologies [ 103 , 104 , 105 , 106 , 107 , 108 , 109 , 110 , 111 ]—along with recent investigations involving oxidation of alcohols and the subsequent trapping of carbonyl intermediates with appropriate nucleophiles in a one-pot operation. [ 112 ]—herein, we report an efficient and environmentally benign TOPs for the Biginelli reaction, starting directly from alcohols, using HPAILs as catalysts and NaNO 3 as an oxidant under MW and solvent-free conditions ( Scheme 1 ).…”