The forests of southeastern North America are influenced by a variety of disturbances including fire and insect outbreaks. In this paper, we discuss the role of disturbances in structuring forest landscapes with particular emphasis placed on the reciprocal interaction between forest structure and outbreaks of the southern pine beetle (Dendroctonus frontalis Zimmermann). We highlight work in which we are currently involved to illustrate the importance and utility of using spatially explicit forest modeling as a tool for understanding forest-insect interactions and its potential role in determining management strategies.