An Effect of Cardioprotective Activity in Various Medicinal Plants–a Review

Abstract

Siddha system of medicines is known for its herbal in origin. Herbal plays a major role in treating acute and chronic diseases. Cardiovascular diseases (CVDs) is the life-threatening disease that contributes a leading cause of death day by day across the world.A change in lifestyle modification is the one of the risks of CVDs. This review paper attempts to facilitate the cardioprotective activity by providing different types of medicinal plants and its botanical distribution, description, chemical constituents and pharmacological activity. Few important herbs will protect the human being from CVDs and gives health and quality of life. In this paper, the authors explores the effect of cardioprotective activity in medicinal plants as follows, Terminalia chebula (Kadukkai), Piper longum (Thippili), Zingiber officinale (Inji), Tinospora cordifolia (Seenthil), Asparagus racemosus (Thanneervitan), Embelia ribes (Vaaivilangam), Andrographis paniculata (Nilavembu), Nelumbo nucifera (Thaamarai), Allium sativum (Vellaipoondu), Bauhinia variegata (Mantharai).

Quantitative Determination of Andrographolide and Related Compounds in Andrographis paniculata Extracts and Biological Evaluation of Their Anti-Inflammatory Activity

“…Using UV and ELSD detection and washing the column for 10 min with MeOH, purity of each compound has been estimated to be superior to 99%. Further identification by NMR spectroscopy ( 1 H, 13…”

“…Using UV and ELSD detection and washing the column for 10 min with MeOH, purity of each compound has been estimated to be superior to 99%. Further identification by NMR spectroscopy ( 1 H, 13 (Figure 4) were obtained by treatment of 1 according to the procedure described in the literature [30] (Scheme 1).…”

“…Using UV and ELSD detection and washing the column for 10 min with MeOH, purity of each compound has been estimated to be superior to 99%. Further identification by NMR spectroscopy ( 1 H, 13 (Figure 4) were obtained by treatment of 1 according to the procedure described in the literature [30] (Scheme 1). Compound 7 came from the standard isomerization of Compound 5 and the semi-synthetic Compounds 8 and 9 were obtained after treatment of 1 with MeONa in MeOH [31] at room temperature (Scheme 2) according to the mechanism proposed in Scheme 3.…”

“…Extracted compounds were characterized by standard spectral methods, NMR, mass Spectroscopy (ESIMS) and high resolution mass spectroscopy (HRMS), and conform to already-described data [33]. 13.0 Hz, J 6B,7B 4.0 Hz, H6B), 1.28-1.12 (2H, m, H1), 1.07 (3H, s, H18), 0.76 (3H, s, H20). 13…”

“…is widely used as medicinal herb in traditional medicine [1][2][3]. Diterpenoid lactones isolated from these extracts have been the subject of intensive investigations and are reported to exhibit a wide spectrum of biological activities, including antibacterial [4], anti-inflammatory [5][6][7][8], hepatoprotective [9][10][11], neuroprotective [12], cardioprotective [13,14] and anticancer properties [15,16]. Andrographolide 1 (Figure 1) has been reported to be the main active compound in the plant [17,18].…”