SummarySecuring an e‐commerce system using epidemic mathematical modeling with neural networks involves adapting epidemiological principles to combat the spread of misinformation. Just like how epidemiologists track the spread of diseases through populations, we can track the dissemination of fake news through online platforms. By modeling how fake news spreads, we gain insights into its propagation patterns, enabling us to develop more effective countermeasures. Neural networks, with their ability to learn from data, play a crucial role in this process by analyzing vast amounts of information to identify and mitigate the impact of fake news. One potential disadvantage of using epidemic mathematical modeling with neural networks to secure e‐commerce systems is the complexity of the approach. The epidemic‐based recurrent long short‐term memory (E‐RLSTM) technique addresses the complexity and evolving nature of fake news propagation by leveraging the strengths of recurrent neural networks (RNNs), specifically long short‐term memory (LSTM) units, within an epidemic modeling framework. One advantage of using epidemic mathematical modeling with neural networks to secure e‐commerce systems is its proactive nature. One significant finding in employing this approach is the ability to uncover hidden connections and correlations within the data. E‐RLSTM stands out by capturing temporal dynamics and integrating epidemic parameters into its LSTM architecture, ensuring robustness and adaptability in detecting and combating fake news within e‐commerce systems, outperforming other techniques in accuracy and performance. Description of the NSL‐KDD dataset offers easy access to a valuable repository for benchmarking cyber security. Contained within are more than 120,000 authentic samples of cyber‐attacks across 41 distinct categories, providing an excellent environment for testing intrusion detection systems.