2020
DOI: 10.1039/c9ra09446f
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An effective hydroxylation route for a highly sensitive glucose sensor using APTES/GOx functionalized AlGaN/GaN high electron mobility transistor

Abstract: A highly sensitive glucose sensor based on AlGaN/GaN high electron mobility transistor (HEMT) has been fabricated.

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Cited by 13 publications
(6 citation statements)
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“…By using virus DNA as a biomarker, the genetic information can be stored significantly compared with RNA. The higher hydroxyl group built in virus DNA resulted in higher stability during the hybridization process 7,8 . Our probe has a higher binding affinity when immobilized on the functionalized surface electrode, especially on AuNPs.…”
Section: Introductionmentioning
confidence: 91%
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“…By using virus DNA as a biomarker, the genetic information can be stored significantly compared with RNA. The higher hydroxyl group built in virus DNA resulted in higher stability during the hybridization process 7,8 . Our probe has a higher binding affinity when immobilized on the functionalized surface electrode, especially on AuNPs.…”
Section: Introductionmentioning
confidence: 91%
“…The higher hydroxyl group built in virus DNA resulted in higher stability during the hybridization process. 7,8 Our probe has a higher binding affinity when immobilized on the functionalized surface electrode, especially on AuNPs. Besides AuNPs, carbon quantum dots (CDs) can also be a conductivity enhancer linked with great chemical linkers such as 3-aminopropyl triethoxysilane (APTES) due to their abundant hydroxyl group.…”
Section: Introductionmentioning
confidence: 97%
“…The adsorption of ions causes a change in the conductance after interacting with the target analytes, which ultimately changes the potential gradient in the solution. The changes in the surface potential over the gate region due to adsorption cause the change in the drain current subsequently [8,9]. While comparing with Si-ion sensitive field-effect transistor (Si-ISFET), AlGaN/GaN HEMT possesses superior mobility, 2DEG charge carrier concentration, and much better performance to attain maximum sensitivity [10,11].…”
Section: Introductionmentioning
confidence: 99%
“…The aminofunctional organosilane material γ-APTES has been widely used as a sensing membrane in biomedical sensors due to its ability to facilitate amino groups on its surface to bind with hydrogen ions. [1][2][3][4] By detecting hydrogen ions, many biological species, such as pH value, [5][6][7][8] glucose, [9][10][11][12] cells, [13][14][15] and dopamine, 16,17) can be detected. On the other hand, nanostructures such as nanowires (NWs) or nanotubes have been demonstrated to have excellent biomedical sensing properties.…”
Section: Introductionmentioning
confidence: 99%