An efficient method to prepare magnetic hydroxyapatite–functionalized multi-walled carbon nanotubes nanocomposite for bone defects

Afroze, Jannatul Dil; Abden, M.J.; Islam, Mohammad Aminul

doi:10.1016/j.msec.2018.02.002

Cited by 19 publications

(11 citation statements)

References 54 publications

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“…The study was carried out in vitro with the aim of improving the mechanical properties of HA without modifying its structure. In fact, the HA, which contains carbon, seems to have greater similarity with the inorganic phase of the bone [ 77 ]. The fMWCNT prevents the HA from decomposing into α-TCP and Ca2P2O7, and it promotes the porosity of the composite, which is essential for the growth of cells.…”

Section: Bone Substitutes and Graftmentioning

confidence: 99%

“…The fMWCNT prevents the HA from decomposing into α-TCP and Ca2P2O7, and it promotes the porosity of the composite, which is essential for the growth of cells. This combination of HA with 0.5 wt% low dose fMWCNT is favorable for improving mechanical strength by approximately 317.5%, hardness by 172.4% and fracture strength by 237% [ 77 ]. This nanocomposite’s favorable application, as has been demonstrated, is when the bone will be a load-bearing support for implants [ 77 ].…”

Section: Bone Substitutes and Graftmentioning

confidence: 99%

“…This combination of HA with 0.5 wt% low dose fMWCNT is favorable for improving mechanical strength by approximately 317.5%, hardness by 172.4% and fracture strength by 237% [ 77 ]. This nanocomposite’s favorable application, as has been demonstrated, is when the bone will be a load-bearing support for implants [ 77 ]. Bone materials, such as β-TCP, have the ability to induce bone regeneration through the release of Ca ions [ 78 ].…”

Section: Bone Substitutes and Graftmentioning

confidence: 99%

“…Research has been developed for a long time to finalize and improve the mechanical properties and osteoinductivity of alloplasts. The combination of HA conf MWCNT 0.5% wt appears to be an appropriate combination as it improves mechanical strength and hardness; however, it remains a bio-scaffold with osteoconductive properties even though it has been claimed that this combination gives a scaffold with magnetic properties that will help to bring the growth factors into the implant site [ 77 ]. There are authors who give importance to osteoconductivity [ 342 , 343 ], but others think that poor osteoinductivity has often led to lower expectations in bone regeneration [ 175 , 344 ].…”

Section: Bone Substitutes and Teeth Graftmentioning

confidence: 99%

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Innovative Concepts and Recent Breakthrough for Engineered Graft and Constructs for Bone Regeneration: A Literature Systematic Review

et al. 2022

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Background: For decades, regenerative medicine and dentistry have been improved with new therapies and innovative clinical protocols. The aim of the present investigation was to evaluate through a critical review the recent innovations in the field of bone regeneration with a focus on the healing potentials and clinical protocols of bone substitutes combined with engineered constructs, growth factors and photobiomodulation applications. Methods: A Boolean systematic search was conducted by PubMed/Medline, PubMed/Central, Web of Science and Google scholar databases according to the PRISMA guidelines. Results: After the initial screening, a total of 304 papers were considered eligible for the qualitative synthesis. The articles included were categorized according to the main topics: alloplastic bone substitutes, autologous teeth derived substitutes, xenografts, platelet-derived concentrates, laser therapy, microbiota and bone metabolism and mesenchymal cells construct. Conclusions: The effectiveness of the present investigation showed that the use of biocompatible and bio-resorbable bone substitutes are related to the high-predictability of the bone regeneration protocols, while the oral microbiota and systemic health of the patient produce a clinical advantage for the long-term success of the regeneration procedures and implant-supported restorations. The use of growth factors is able to reduce the co-morbidity of the regenerative procedure ameliorating the post-operative healing phase. The LLLT is an adjuvant protocol to improve the soft and hard tissues response for bone regeneration treatment protocols.

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Section: Bone Substitutes and Graftmentioning

confidence: 99%

Section: Bone Substitutes and Graftmentioning

confidence: 99%

Section: Bone Substitutes and Graftmentioning

confidence: 99%

Section: Bone Substitutes and Teeth Graftmentioning

confidence: 99%

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Innovative Concepts and Recent Breakthrough for Engineered Graft and Constructs for Bone Regeneration: A Literature Systematic Review

et al. 2022

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“… 4 In addition, the hydroxyl groups with polar effects on the surface can be associated with cell membrane proteins through hydrogen bonding, showing good biocompatibility. 5 At present, the introduction of HA into the PLA matrix using the idea of a material composite has been adopted by researchers. For example, Lu et al 6 found that the addition of HA effectively improved the tensile strength and tensile modulus of PLA composite films.…”

Section: Introductionmentioning

confidence: 99%

In Situ Grown Nanohydroxyapatite Hybridized Graphene Oxide: Enhancing the Strength and Bioactivity of Polymer Scaffolds

Chen

Guo

et al. 2022

ACS Omega

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Graphene oxide (GO) and nanohydroxyapatite (nHA) are usually used for improving the strength and bioactivity of polymer scaffolds. However, due to the nano-aggregation effect, these applications often face the problems of uneven dispersion and poor interface bonding. In this work, their hybrids (GO@nHA) were constructed by combining chemical modification and in situ growth methods, realizing the perfect combination of nHA and GO. First, the functionalization of GO was realized through oxidative self-polymerization of dopamine (DA), and the product was denoted GO@DA. Furthermore, the in situ growth of nHA on GO@DA was induced by hydrothermal reactions to prepare GO@nHA hybrids. Then, the obtained hybrid was added to the polymer matrix, and a composite scaffold was prepared through a selective laser sintering process. The results demonstrated that with the addition of GO@DA and GO@nHA, the ultimate strength was increased to 16.8 and 18.6 MPa, respectively, which is 66 and 84% higher than the 10.1 MPa of the polylactic acid (PLA) scaffold. In addition, composite scaffolds exhibited good biomineralization ability in vitro and also promoted the adhesion and proliferation of MG63 cells.

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Fabrication of HAP/Ag/SSD ternary nanocomposite and its antibacterial properties

et al. 2020

J Sol-Gel Sci Technol

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An efficient method to prepare magnetic hydroxyapatite–functionalized multi-walled carbon nanotubes nanocomposite for bone defects

Cited by 19 publications

References 54 publications

Innovative Concepts and Recent Breakthrough for Engineered Graft and Constructs for Bone Regeneration: A Literature Systematic Review

Innovative Concepts and Recent Breakthrough for Engineered Graft and Constructs for Bone Regeneration: A Literature Systematic Review

In Situ Grown Nanohydroxyapatite Hybridized Graphene Oxide: Enhancing the Strength and Bioactivity of Polymer Scaffolds

Fabrication of HAP/Ag/SSD ternary nanocomposite and its antibacterial properties

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