An efficient synthesis of 3β,14β-dihydroxy-5α-androst-15-en-17-one

Abstract

An efficient four-step method has been developed for the synthesis of 3 β,14 β-dihydroxy-5 α-androst-15-en-17-one from a common androstane derivative. The X-ray crystal structures of the alkenes, the epoxide and the 14-hydroxy compound have been determined.