An electrochemical sensor for clozapine at ruthenium doped TiO2 nanoparticles modified electrode

Shetti, Nagaraj P.; Nayak, Deepti S.; Malode, Shweta J.; Kulkarni, Raviraj M.

doi:10.1016/j.snb.2017.03.102

Cited by 134 publications

(34 citation statements)

References 46 publications

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“…[41] The effective surface area of GrÀ W/GCE was calculated as 0.79 cm 2 . [42] This surface area was about 8 times higher than the surface area (0.1 cm 2 ) of a bare GCE. As shown in Figure 4D, the linear plot between the log of scan rate vs. peak potentials (E pa and E pc ) indicated that the redox reaction of [Fe(CN) 6 ] 3À /4À was a diffusion controlled process because the peak potentials were shifted with the increasing of scan rates from 10 to 500 mV/s.…”

Section: Hr-tem Edx and Zeta Potential Analysismentioning

confidence: 82%

Selective Electrochemical Sensing of NADH and NAD⁺ Using Graphene/Tungstate Nanocomposite Modified Electrode

2020

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Reduced form of β‐nicotinamide adenine dinucleotide (NADH) and its oxidized form (NAD+) are the main cofactors involved in more than 300 dehydrogenase reactions. NAD+ is one of the important oxidizing agent for the oxidation of alcohol, aldehyde and ketones. Similarly, NADH has been used for the treatment of Alzheimer and Parkinson's diseases. Herein, we have reported synthesis of graphene flakes by electrochemical exfoliation of graphite in sodium tungstate solution. It was found that tungstate (WO42−) and hydroxyl (OH−) ions were intercalated into graphite layers and enabled the production of graphene flakes. As‐obtained graphene flakes were characterized by UV‐Visible (UV‐Vis), Fourier transform infrared (FT‐IR), Raman, Field emission scanning electron microscopy (FE‐SEM), Energy dispersive X‐ray (EDX) and High‐resolution transmission electron microscopies (HR‐TEM). FT‐IR, Raman and EDX analysis were confirmed that tungstate (WO42−) ions were present on the surface of graphene flakes. Moreover, graphene‐WO42− (Gr−W) dispersion was prepared by probe‐sonication to form a thin‐film on the surface of glassy carbon electrode (Gr−W/GCE). Interestingly, Gr‐W modified GCE reduced the overpotentials of NADH oxidation and NAD+ reduction. This new senor was also showed linear responses for NADH and NAD+ from 10–270 μM and 100–500 μM, respectively. Furthermore, the selectivity of the Gr−W/GCE was tested in the presence of L‐tyrosine, L‐isoleucine, L‐alanine, glutathione, dopamine (DA), ascorbic acid (AA), uric acid (UA), oxalic acid (OA), glucose, hydrogen peroxide (H2O2), acetaminophen (PA), potassium chloride (KCl) and sodium chloride (NaCl). It was found that selective detection of both NADH and NAD+ could be achieved by using Gr−W/GCE. Finally, the real application of the sensor was demonstrated by accurately detecting spiked NADH concentrations in human blood serum. The recovery analysis was also confirmed that Gr−W/GCE could be useful to detect NADH in biological samples.

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Section: Hr-tem Edx and Zeta Potential Analysismentioning

confidence: 82%

Selective Electrochemical Sensing of NADH and NAD⁺ Using Graphene/Tungstate Nanocomposite Modified Electrode

2020

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“…Here, C 0 = 0.05, n = 1, D 0 = 7.6 × 10 −6 cm 2 s −1 . On substituting these values, the active surface area was calculated to be 0.056 cm 2 on a modified Au electrode [42]. The CV response was recorded for a modified Au electrode in 0.25 mM 2,4-DNT in 0.1 M, PBS (pH = 7.4), respectively, at a scan rate of 0.0050 mV/s.…”

Section: Cyclic Voltammetrymentioning

confidence: 99%

Construction of Silver Quantum Dot Immobilized Zn-MOF-8 Composite for Electrochemical Sensing of 2,4-Dinitrotoluene

et al. 2019

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In the present study, we report a highly effective electrochemical sensor for detecting 2,4-dinitrotoluene (2,4-DNT). The amperometric determination of 2,4-DNT was carried out using a gold electrode modified with zinc–metal organic framework-8 and silver quantum dot (Zn-MOF-8@AgQDs) composite. The synthesized nanomaterials were characterized by using transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR) and X-ray powder diffraction (XRD). The synthesized nanocomposite proved to be efficient in electro-catalysis thereby reducing the 2,4-DNT. The unique combination present in Zn-MOF-8@AgQDs composite offered an excellent conductivity and large surface area enabling the fabrication of a highly sensitive (−0.238 µA µM−1 cm−2), selective, rapid and stable 2,4-DNT sensor. The dynamic linear range and limit of detection (LOD) was about 0.0002 µM to 0.9 µM and 0.041 µM, respectively. A 2,4-DNT reduction was also observed during the linear sweep voltammetry (LSV) experiments with reduction peaks at −0.49 V and −0.68 V. This is an unprecedented report with metal organic framework (MOF) composite for sensing 2,4-DNT. In addition, the presence of other species such as thiourea, urea, ammonia, glucose, and ascorbic acid displayed no interference in the modified electrode suggesting its practicability in various environmental applications.

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“…This can be attributed to large surface‐volume ratio of their nano structure. Additionally, they exhibit noteworthy selectivity which is of utmost importance in the current study . Also due to paucity of literature of MO‐nps composites as modifiers for RS detection, in this work we have exploited its application with the utilization of maghemite nano‐particles.…”

Section: Introductionmentioning

confidence: 99%

Voltammetric Study and Rapid Quantification of Resorcinol in Hair Dye and Biological Samples Using Ultrasensitive Maghemite/MWCNT Modified Carbon Paste Electrode

Manasa¹,

Bhakta

Mekhalif

et al. 2019

Electroanalysis

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Increased concern over the risk resorcinol (RS) pose to ecology and humans, led to its position in European Union Category 1 list of endocrine disruptors. Legal measures restricted RS utilization and hence crucial to monitor its levels in the environment. Herein we report development of highly efficient and economically viable electrochemical sensor for quantitative determination of RS based on 77Maghemite/MultiWall Carbon Nanotube (M/MWCNT) modified carbon paste electrode. M/MWCNT was synthesized via strategic IR irradiation for the first time, a promising approach to overcome other complicated chemical routes. Powder X‐ray diffraction (PXRD), Transmission electron microscopy (TEM), Field emission scanning electron microscopy (FESEM) and Energy dispersive X‐ray (EDX) were used for characterization. Using Differential Pulse Voltammetry (DPV), we report the lowest detection limit at 0.02 μM. The potential application of the sensor was accomplished as a result of excellent recoveries made from real samples fortified with RS. Results indicated the proficiency of the sensor reliable for rapid, onsite monitoring of RS water contamination and in biological matrices.

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An electrochemical sensor for clozapine at ruthenium doped TiO2 nanoparticles modified electrode

Cited by 134 publications

References 46 publications

Selective Electrochemical Sensing of NADH and NAD⁺ Using Graphene/Tungstate Nanocomposite Modified Electrode

Selective Electrochemical Sensing of NADH and NAD⁺ Using Graphene/Tungstate Nanocomposite Modified Electrode

Construction of Silver Quantum Dot Immobilized Zn-MOF-8 Composite for Electrochemical Sensing of 2,4-Dinitrotoluene

Voltammetric Study and Rapid Quantification of Resorcinol in Hair Dye and Biological Samples Using Ultrasensitive Maghemite/MWCNT Modified Carbon Paste Electrode

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An electrochemical sensor for clozapine at ruthenium doped TiO2 nanoparticles modified electrode

Cited by 134 publications

References 46 publications

Selective Electrochemical Sensing of NADH and NAD+ Using Graphene/Tungstate Nanocomposite Modified Electrode

Selective Electrochemical Sensing of NADH and NAD+ Using Graphene/Tungstate Nanocomposite Modified Electrode

Construction of Silver Quantum Dot Immobilized Zn-MOF-8 Composite for Electrochemical Sensing of 2,4-Dinitrotoluene

Voltammetric Study and Rapid Quantification of Resorcinol in Hair Dye and Biological Samples Using Ultrasensitive Maghemite/MWCNT Modified Carbon Paste Electrode

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Selective Electrochemical Sensing of NADH and NAD⁺ Using Graphene/Tungstate Nanocomposite Modified Electrode

Selective Electrochemical Sensing of NADH and NAD⁺ Using Graphene/Tungstate Nanocomposite Modified Electrode