An emerging deep eutectic solvent based on halogen-bonds

Abstract

A new deep eutectic solvents (DES) driven by halogen-bond was exploited. A family of eutectic mixtures in liquid state were obtained by combination of quaternary ammonium salts and dihalogens. The...

The Most Potent Natural Pharmaceuticals, Cosmetics, and Food Ingredients Isolated from Plants with Deep Eutectic Solvents

“…Depending on the character of the hydrogen bond acceptor (HBA) and the hydrogen bond donor (HBD), interactions such as hydrogen bonding, van der Waals interactions, or π–π stacking occur. Recently, novel eutectic systems, namely, eutectic molecular liquids (EMLs), were defined, and several other noncovalent interactions were identified, including not only hydrogen bonding and π–π stacking but also σ-hole (halogen, pnicogen, and tetrel bonds), π-hole, κ-hole, and μ-hole bonding interactions. , There is a huge interest in composing DESs with new and interesting properties as well as in explaining the structure–activity relationship and the interactions occurring between different HBAs and HBDs. − The most valuable feature of DESs seems to be the possibility of obtaining almost unlimited numbers of tailor-made solvents by selecting appropriate HBDs and HBAs. Additionally, many DESs (also named natural deep eutectic solvents, NADESs) are bioderived, green, biocompatible, biodegradable, and nontoxic chemicals, unlike classic solvents (including solvents belonging to volatile organic compounds, VOCs) or some ILs.…”

Unexpectedly Superhigh Toxicity of Superbase-Derived Deep Eutectic Solvents albeit High Efficiency for CO2 Capture and Conversion

“…The emergence of deep eutectic solvents (DESs) has aroused great interest in the fields of gas capture/utilization, − biomass conversion, − material preparation, , energy storage, − and batteries recovery. − DESs are discovered by Abbott et al to show liquid near room temperature in 2003 exemplifying by ChCl:urea, ChCl:methyl urea, ChCl:dimethyl urea, ChCl:thiourea, ChCl:acetamide, ChCl:benzamide, and ChCl:tetramethyl urea . DESs are the liquid mixture of two or more compounds interacting through hydrogen bonds or halogen bonds. ,, The individual compounds are known as hydrogen bond donors (HBDs) or hydrogen bond acceptors (HBAs). Not only DESs show similar benign properties to the ionic liquids (ILs), such as low volatility, low flammability, and low melting point, but also it has the unique advantages of a simple synthesis procedure, high atomic utilization rate, and high product purity. − Due to these favorable properties of DESs, they have been paid much attention in many areas. − ,− …”

“…19 DESs are the liquid mixture of two or more compounds interacting through hydrogen bonds or halogen bonds. 9, 20,21 The individual compounds are known as hydrogen bond donors (HBDs) or hydrogen bond acceptors (HBAs). Not only DESs show similar benign properties to the ionic liquids (ILs), such as low volatility, low flammability, and low melting point, but also it has the unique advantages of a simple synthesis procedure, high atomic utilization rate, and high product purity.…”

aquo-DESs: WATER-BASED BINARY NATURAL DEEP EUTECTIC SOLVENTS

“…The interactions occurring between the HBD and the HBA as well as between the same HBA-HBA and HBD-BHD lead to an impossible regular crystal lattice formation, therefore to liquid systems starting from high melting point components [13][14][15][16]. Also, other weak forces, such as halogen bonds or electrostatic interactions can occur in these liquids where the entropy and the inhomogeneity of the structures lead to liquids at the proper molar ratio, indicated as eutectic point [17][18][19]. The molecules that are reported in literature as capable for DESs formation are mainly carboxylic acids, polyols, alcohols, and so on as HBD, while ammonium or phosphonium salts, zwitterionic inner salts or neutral molecules such as acetamide as well as inorganic salts (also hydrates) are reported to be efficacious HBAs in the DESs formation [11,[20][21][22][23].…”