2021
DOI: 10.1101/2021.02.13.430688
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An exon junction complex-independent function of Barentsz in neuromuscular synapse growth

Abstract: The exon junction complex controls the translation, degradation and localization of spliced mRNAs, and three of its four core subunits also play a role in splicing. Here we show that the fourth subunit, Barentsz, has distinct biological functions within and separate from the exon junction complex in neuromuscular development. Barentsz controls the distribution of mitochondria in larval muscles, a function that also depends on other subunits of the exon junction complex and that is not rescued by a transgene in… Show more

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