The installation of 3 × 50 MW (150 MW DC) large utility scale solar power plant is ground based using ventilated polycrystalline module technology with fixed tilt angle of 28°in a 750-acre land, and the site is located about 115 km northeast of Karachi, Pakistan, near the town of ThanoBula Khan, Nooriabad, Sindh. This plant will be connected to the utility distribution system through a national grid of 220 kV outgoing double-loop transmission line. The 3 × 50 MW solar PV will be one of the largest tied grid-connected power projects as the site is receiving a rich average solar radiation of 158.7 kW/h/m 2 /month and an annual average temperature of about of 27°C. The analysis highlights the preliminary design of the case project such as feasibility study and PV solar design aspects and is based on a simulation study of energy yield assessment which has all been illustrated. The annual energy production and energy yield assessment values of the plant are computed using the PVSYST software. The assumptions and results of energy losses, annual performance ratio (PR) 74.73%, annual capacity factor 17.7%, and annual energy production of the plant at 232,518 MWh/year are recorded accordingly. Bear in mind that reference recorded data indicates a good agreement over the performance of the proposed PV power plant.