“…Since then, heat transfer in micro-channels has been extensively studied, however, published results are still inconsistent; some studies have found the average Nusselt number to be Reynolds number dependent in the laminar regime [10][11][12], some recorded lower Nusselt numbers [13][14][15] while some recorded higher Nusselt numbers [16][17][18]. Reviews on experimental and numerical studies of heat transfer in microchannels published by Mokrani, Bourouga, Castelain and Peerhossaini [19], Hetsroni, Mosyak, Pogrebnyak and Yarin [20], Rosa, Karayiannis and Collins [21] and Sobhan and Garimella [22] confirm the very large scatter in published results and attribute this to "scaling effects", which arise from neglecting phenomenon which are insignificant in conventional sized channels but become significant with the high channel wall surface to fluid volume ratio in microchannel flow.…”