2013
DOI: 10.4172/2153-2435.1000254
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An Explicit Review on Quantitative Estimation of Candesartan Cilexetil Employing Various Analytical Techniques

Abstract: Pha rm a c e u tic a An a ly t ic a A cta

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Cited by 8 publications
(6 citation statements)
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“…Candesartan cilexetil (CC) is a selective, reversible, competitive angiotensin II receptor-1 antagonist, and it's used for the management of hypertension, heart failure, and myocardial infarction. It is also used in patients with impaired left ventricular systolic function, either when ACE inhibitors are not tolerated, or in addition to ACE inhibitors (14,15) .…”
Section: Introductionmentioning
confidence: 99%
“…Candesartan cilexetil (CC) is a selective, reversible, competitive angiotensin II receptor-1 antagonist, and it's used for the management of hypertension, heart failure, and myocardial infarction. It is also used in patients with impaired left ventricular systolic function, either when ACE inhibitors are not tolerated, or in addition to ACE inhibitors (14,15) .…”
Section: Introductionmentioning
confidence: 99%
“…It contains two acidic functional groups: a carboxyl and tetrazole moieties and its pKa values were calculated to be 4.22 in its unionized form and 4.24 in its ionized form (Beale et al 2010;Bandyopadhyay et al 2013). The CC is a racemic mixture containing one chiral center at the ester group.…”
Section: Introductionmentioning
confidence: 99%
“…The melting point of candesartan cilexetil powder was measured by putting a small amount of candesartan cilexetil powdered drug into a capillary glass tube that sealed from one side and opened from another side, then the tube placed in digital melting point instrument and temperature of melting was recorded, when complete melting of powdered drug occurs [6].…”
Section: Methodsmentioning
confidence: 99%