An immobilized carboxyl containing metal-organic framework-5 stationary phase for open-tubular capillary electrochromatography

Bao, Tao; Tang, Pingxiu; Mao, Zhenkun; Chen, Zilin

doi:10.1016/j.talanta.2016.03.089

Cited by 47 publications

(20 citation statements)

References 39 publications

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“…In this work, the main influencing factors of EOF were investigated, including pH, organic modifier, and concentration of buffer solution. The EOF was calculated using the formula:

μ_{eo} = \frac{{normalL}_{normald} {normalL}_{normalt}}{{Vt}_{0}}

. Thiourea was chosen as a neutral marker.…”

Section: Resultsmentioning

confidence: 99%

Open‐tubular capillary electrochromatography using carboxylatopillar[5]arene as stationary phase

Kong

Chen

2017

Electrophoresis

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Pillar[n]arenes have achieved much interest in material chemistry and supramolecular chemistry due to unusual pillar shape structure and high selectivity toward guest. However, pillar[n]arenes have not yet been applied in capillary electrochromatography. This work at first time reports that carboxylatopillar[5]arene is used as a stationary phase in open-tubular capillary electrochromatography. Carboxylatopillar[5]arene not only possess the advantages of pillar[n]arenes but also provide free carboxy groups for immobilizing on the inner wall of capillary column via covalent bonding. The characterization of SEM and FT-IR indicated that carboxylatopillar[5]arene was successfully grafted on the inner wall of capillary. The baseline separation of model analytes including neutral, basic, and acidic compounds, nonsteroidal anti-inflammatory drugs and dansyl-amino acids have been achieved thanks to the electron-rich cavity of carboxylatopillar[5]arene and hydrophobic interactions between the analytes and stationary phase. The intraday, interday, and column-to-column precisions (RSDs) of retention time and peak area for the neutral analytes were all less than 3.34 and 9.65%, respectively. This work indicates that pillar[n]arenes have great potential in capillary electrochromatography as novel stationary phase.

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“…In this work, the main influencing factors of EOF were investigated, including pH, organic modifier, and concentration of buffer solution. The EOF was calculated using the formula:

μ_{eo} = \frac{{normalL}_{normald} {normalL}_{normalt}}{{Vt}_{0}}

. Thiourea was chosen as a neutral marker.…”

Section: Resultsmentioning

confidence: 99%

Open‐tubular capillary electrochromatography using carboxylatopillar[5]arene as stationary phase

Kong

Chen

2017

Electrophoresis

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“…Bao and co‐workers employed MOF‐5, also named as isoreticular MOF (IRMOF‐1), for the separation of substituted benzenes and small aromatic acidic and basic compounds . The MOF‐5 structure, built from the reticulating organic dicarboxylate group and the octahedral Zn‐O‐C lattice, utilised the dicarboxylate benzene struts to interact with the benzene structures of the analytes for their separation.…”

Section: Developments In Stationary Phase Materialsmentioning

confidence: 99%

“…Silanisation of the inner wall of fused silica capillaries is a well‐known derivatisation reaction using organofunctional alkoxysilanes to react with the hydroxyl groups of silica and establish covalent bonds between the inorganic silicate surface with an organic functionality. For example, the use of aminosilanes (3‐aminopropyl)triethoxysilane (APTES) or (3‐aminopropyl)‐trimethoxysilane (APTMS) generate terminal aminopropyl‐ groups whereby other condensation reactions can take place to covalently attach the SP . An elegant coating approach was proposed by Bao and co‐workers for the immobilisation of MOF‐5 framework.…”

Section: Developments In Coating Strategies and Fabrication Techniquesmentioning

confidence: 99%

“…An elegant coating approach was proposed by Bao and co‐workers for the immobilisation of MOF‐5 framework. The process involved initial silanisation with APTES, functionalisation with aldehyde groups by reaction with glutaraldehyde, then further oxidation to form carboxyl terminated surface . The MOF was built onto the surface by an epitaxial growth process utilising the COOH‐ terminals as reaction points to bind the Zn clusters of the MOF.…”

Section: Developments In Coating Strategies and Fabrication Techniquesmentioning

confidence: 99%

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Recent developments in open tubular capillary electrochromatography from 2016 to 2017

2017

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Recent developments in open tubular capillary electrochromatography from 2016 to 2017Interest in open-tubular capillary electrochromatography (OT-CEC) continues to thrive because of the inherent advantage of OT-CEC combining the high efficiency of capillary electrophoresis and the high selectivity of high performance liquid chromatography. For the period 2016 to 2017, novel materials have been developed as first-time stationary phases for OT-CEC and are grouped in this review as polymer-based materials, frameworks, nanoparticles, graphene-based materials, and biomaterials. Coating and fabrication methods mostly rely on covalent coating strategies while non-covalent immobilisation strategies like electrostatic assembly are notably still being employed. The concern of overcoming phase ratio challenges in OT-CEC coatings have also generated adoption of combined coating strategies including multi-layering, layer-by-layer self-assembly and methods adapted from nanofilm fabrications like epitaxial growth, liquid phase deposition, or nucleation of crystal growth. The emergence of non-conventional coating characterisation methods such as transmission electron microscopy, X-ray diffraction or X-ray photoelectron spectroscopy is also discussed.

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“…Very recently, Bao et al. first reported the in situ synthesis of MOF‐5 for immobilization on the COOH‐terminated capillary and subsequent separation of neutral substituted benzenes. The corresponding mechanism involved π‐π interactions between the aromatic rings of the analytes and the struts in the framework of MOF‐5 in which octahedral Zn‐O‐C clusters had been linked by dicarboxylate benzene struts as well as hydrophobic interactions resulting from their extended network and porous structure.…”

Section: Nanomaterials Applications In Capillary Electrochromatographymentioning

confidence: 99%

Recent applications of nanomaterials in capillary electrophoresis

et al. 2017

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Nanomaterials have found an important place in Analytical Chemistry and, in particular, in Separation Science. Among them, metal-organic frameworks, magnetic and non-magnetic nanoparticles, carbon nanotubes and graphene, as well as their combinations, are the most important nanomaterials that have been used up to now. Concerning capillary electromigration techniques, these nanomaterials have also been used as both pseudostationary phases in electrokinetic chromatography (EKC) and as stationary phases in microchip capillary electrophoresis (CE) and capillary electrochromatography (CEC), as a result of their interesting and particular properties. This review article pretends to provide a general and critical revision of the most recent applications of nanomaterials in this field (period 2010-2017).

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An immobilized carboxyl containing metal-organic framework-5 stationary phase for open-tubular capillary electrochromatography

Cited by 47 publications

References 39 publications

Open‐tubular capillary electrochromatography using carboxylatopillar[5]arene as stationary phase

Open‐tubular capillary electrochromatography using carboxylatopillar[5]arene as stationary phase

Recent developments in open tubular capillary electrochromatography from 2016 to 2017

Recent applications of nanomaterials in capillary electrophoresis

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