“…16 -18 In breast cancer patients with histologically confirmed N0 nodes, the same incidence is 12%-20.6%, 19,20 whereas non-small-cell lung cancer patients have a much higher incidence of micrometastases, ranging from 56.4%-70%. 21,22 There is also some disagreement among published studies on the prognostic impact of micrometastases. In patients with colon cancer, Sasaki et al and Liefers et al 18,23 report that the presence of micrometastases increases the risk of relapse, so affecting the prognosis, in contrast to other authors 16,17,24,25 claims.…”