2012
DOI: 10.1002/mrm.23252
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An improved coverage and spatial resolution—using dual injection dynamic contrast‐enhanced (ICE‐DICE) MRI: A novel dynamic contrast‐enhanced technique for cerebral tumors

Abstract: A new dual temporal resolution-based, high spatial resolution, pharmacokinetic parametric mapping method is describedimproved coverage and spatial resolution using dual injection dynamic contrast-enhanced (ICE-DICE) MRI. In a dualbolus dynamic contrast-enhanced-MRI acquisition protocol, a high temporal resolution prebolus is followed by a high spatial resolution main bolus to allow high spatial resolution parametric mapping for cerebral tumors. The measured plasma concentration curves from the dual-bolus data … Show more

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Cited by 31 publications
(56 citation statements)
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“…A similar result was also confirmed in dynamic contrast-enhanced MRI study, 25 which can attain higher resolution than DSC perfusion-weighted MRI. 32 Although vascular permeability differences play a role here in discriminating PCNSL from glioblastoma, the potentially more specific technique of permeability-based dynamic contrast-enhanced MRI is more challenging to implement, which is a benefit of the simpler DSC perfusionweighted MRI based methods used. PSR end and PSR mean were significantly different as well as cCBVR and uCBVR.…”
Section: Discussionmentioning
confidence: 99%
“…A similar result was also confirmed in dynamic contrast-enhanced MRI study, 25 which can attain higher resolution than DSC perfusion-weighted MRI. 32 Although vascular permeability differences play a role here in discriminating PCNSL from glioblastoma, the potentially more specific technique of permeability-based dynamic contrast-enhanced MRI is more challenging to implement, which is a benefit of the simpler DSC perfusionweighted MRI based methods used. PSR end and PSR mean were significantly different as well as cCBVR and uCBVR.…”
Section: Discussionmentioning
confidence: 99%
“…Recently, a new dual temporal resolution-based, high spatial resolution, pharmacokinetic parametric mapping method has been described (31). In the protocol, a high temporal resolution pre-bolus is followed by a high spatial resolution main bolus to allow high spatial resolution parametric mapping for tumors.…”
Section: Introductionmentioning
confidence: 99%
“…3 Figure 1 shows the relationship between the lab time and t stretch calculated using a C p (t) measured from low CA dose, high temporal resolution (LDHT) imaging in a patient with VS. 11 It can be seen that a t stretch interval 80-250 seconds 2 corresponds to a lab time interval 37-157 seconds. The relationship between t stretch and lab time is approximately linear beyond a lab time of $37 seconds, but fluctuates within the first-pass and recirculation phase of the CA bolus.…”
Section: Patlak Plotmentioning
confidence: 99%
“…LDHT DCE-MRI data were collected as part of the dual temporal resolution technique, ICR-DICE, as described previously. 11 Prior to the LDHT DCE series, four consecutive 3D …”
Section: Mrimentioning
confidence: 99%
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