An in vivo photodynamic therapy with diode laser to cell activation of kidney dysfunction

Astuti, Suryani Dyah; Prasaja, Brahma Indra; Prijo, Tri Anggono

doi:10.1088/1742-6596/853/1/012038

Cited by 14 publications

(10 citation statements)

References 9 publications

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“…The biomodulation effect of laser is on the wavelength of visible and near infrared spectrum [19,28]. This study used a laser with a wavelength of 650 nm because it had a good anti-inflammation effect in the clinical study (the synthesis modulation and cytokine pro and inflammation expression [28].…”

Section: Discussionmentioning

confidence: 99%

The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study

Astuti¹,

Victory²,

Mahmud³

et al. 2019

J Adv Vet Anim Res

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Objective:The aim of this study is to determine the effect of laser diode as an alternative treatment on liver dysfunction (in vivo study) that is caused by carbofuran using male mice (Mus musculus) strain Balb/C.Materials and Methods:The samples were divided into three groups, namely, Group C–L– (control group, no treatment), Group C+L– (only treated by carbofuran treatment), and Group C+L+ (treatment group, treated by carbofuran and laser-puncture) with five replications each. After being treated, each liver slice of samples was observed using microscope to get the histology result and then scored.Results:Carbofuran contamination can lead to inflammation of cells and necrosis. The histology results and the scoring test showed that the liver cells repair with the energy dose of laser diode at 0.5 and 1.0 Joule.Conclusion:The optimum energy dose in this study was 1.0 Joule which had the closest score of inflammatory cells and necrosis to normal liver cells.

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Section: Discussionmentioning

confidence: 99%

The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study

Astuti¹,

Victory²,

Mahmud³

et al. 2019

J Adv Vet Anim Res

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“…First day administration of laser therapy showed that the CEJ-AV distance was not different from the healthy group. Various research results show that the laser acts as a stimulator that triggers the de-epitheliazation process and increases vascular permeability [ 12 ]. Both processes are known to inhibit growth factor down-regulation and increase the infiltration of immunocompetent cells [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

“…Photodynamic therapy is a non-invasive therapeutic method that utilizes photons of light energy for medical applications [ 11 , 12 ]. This therapy has been used to treat chronic inflammation and is believed to be an alternative for treating antibiotic-resistant bacteria [ 9 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

Combination effect of laser diode for photodynamic therapy with doxycycline on a wistar rat model of periodontitis

et al. 2021

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Background Periodontitis is a chronic inflammatory disease characterized by progressive damage on the structure of tooth-supporting tissues. The aim of the study is determining the combination photodynamic effect of diode laser 405 nm treatments and the administration of doxycycline 0.1% within 1, 3, 5, and 7 days on a Wistar rat model of periodontitis. Methods Samples were induced with Porphyromonas gingivalis ATCC33277 to allow periodontitis development and were treated with combination of doxycycline and laser diode, then statistical analysis was carried out (One-Way ANOVA test and the post-hoc Duncan test; Kruskal–Wallis test and Mann–Whitney follow-up test for non-parametric data). Samples were divided into five groups, laser exposure used was 405-nm diode laser with energy density of 8 J/cm2. The expression level of histomorphometric was calculated by measuring the number of macrophages, lymphocytes, fibroblasts and the distance between the CEJ-AV. Results The results showed that the combination treatment of doxycycline and laser exposure yielded immunomodulatory effects. The expression level of fibroblast and the distance between CEJ-AV bone showed that the combination of doxycycline and laser therapy exerted healing effect in rat models of periodontitis on day 5 and 7. Conclusion The combination of doxycycline 0.1% and diode laser therapy provides a healing effect in rats models of periodontitis.

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“…Tese expensive treatments can also result in anorexia, headaches, nausea, and dizziness in some people [2,3]. Acupuncture and electric needles have both been used in research for the invasive diagnosis and therapy of organ disease [4][5][6], and noninvasively using light [7][8][9]. Te human body is equipped with an electrical system [10].…”

Section: Introductionmentioning

confidence: 99%

Ameliorative and Renoprotective Effect of Electrical Stimulation on Blood Sugar, Blood Urea Nitrogen (BUN), Creatinine Levels, and the Islets of Langerhans Weight in Diabetic Mice

Suhariningsih

Glory

Khaleyla

et al. 2022

Veterinary Medicine International

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Diabetes mellitus (DM) is a chronic metabolic disease or disorder characterized by high blood sugar levels as well as impaired carbohydrate, lipid, and protein metabolism due to insulin function insufficiency. Insulin deficiency can be caused by impaired or deficient insulin production by Langerhans beta cells in the pancreas or by a lack of responsiveness of the body's cells to insulin. This study aims to the effects of electrostimulation on the ameliorative (improves disease manifestations) or renoprotective (protects the kidneys) in a diabetic rat model using noninvasive (electrical stimulation with the magnetic and nonmagnetic electrode) and invasive (using needles) methods. This study used 25 female rats, with a normal control group (KN), a diabetes control group (KD), a needle treatment group (A), an electro-stimulator treatment group with a magnetic electrode (M), and an ES group with a nonmagnetic electrode (ES) (L). The electro-stimulator used AES-05 with a magnetic field strength of 90 mT at two acupoints, Pishu (BL20) and Shenshu (BL23). The treatment was administered 12 times in one month with a therapy time of 6.6 minutes per session. Body weight and blood sugar levels were compared before and after the treatment. After treatment, the diameter of the islets of Langerhans, as well as levels of creatinine and blood urea nitrogen (BUN), was measured. Furthermore, statistical analysis was performed (α = 0.05). The results of this study showed that electrical stimulation treatments with needle-invasive, noninvasive magnetic electrodes, and nonmagnetic electrodes significantly reduced diabetic rats’ blood glucose levels before and after the treatment. The analysis of the diameter of the islets of Langerhans revealed a significant difference between the treatment groups. The analysis of creatinine levels revealed a significant difference between groups, but creatinine levels in the group with the magnetic electrode (0.58 ± 0.17 mg/dL) were not significantly different from the control group (0.58 ± 0.07 mg/dL). The BUN test results revealed a significant difference compared with the diabetic control group, but no significant difference with the magnetic electrode treatment group. Conclusion. Based on the results, the most effective therapy for diabetes is a noninvasive method with magnetic (M) electrodes.

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An in vivo photodynamic therapy with diode laser to cell activation of kidney dysfunction

Cited by 14 publications

References 9 publications

The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study

The effects of laser diode treatment on liver dysfunction of Mus musculus due to carbofuran exposure: An in vivo study

Combination effect of laser diode for photodynamic therapy with doxycycline on a wistar rat model of periodontitis

Ameliorative and Renoprotective Effect of Electrical Stimulation on Blood Sugar, Blood Urea Nitrogen (BUN), Creatinine Levels, and the Islets of Langerhans Weight in Diabetic Mice

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