An Infant With Firm, Fixed Plaques

Subcutaneous fat necrosis of the newborn: a systematic evaluation of risk factors, clinical manifestations, complications and outcome of 16 children

“…In our study, the main immediate SFN complication was hypercalcaemia, in agreement with previous publications 1,5,7,8,20–28 . Most often, this hypercalcaemia was moderate (< 3 mmol L −1 ) without clinical symptoms.…”

Subcutaneous Fat Necrosis of the Newborn: A Review of 11 Cases

“…An association between SFN and hypercalcemia was first reported in 1956 (10) and 19 cases were found when the world literature was reviewed up to 1990 (2). Since that review, a further 29 cases of SFN have been reported and, although not all were adequately monitored, hypercalcemia was detected in 17 (3–5,7–9,11–28). These descriptions are mainly single case reports and the high frequency of hypercalcemia may be an artifact of publication bias.…”