An Inheritable variant of the innate immune receptor melanoma differentiation‐associated gene 5 promotes clearance of hepatitis C virus

Polymorphisms in melanoma differentiation‐associated gene 5 are not associated with clearance of hepatitis C virus in a European American population

“…In this haplotype, H843/T946, the SNP rs3747517 encoding the H843 variant was also associated with spontaneous HCV clearance whereas the SNP (rs1990760) encoding T946 was not. As discussed in an accompanying Editorial (2), if this finding is true, it broadens knowledge regarding the known innate immune response to HCV.…”