An Initiative to Reduce Preterm Infants Pre-discharge Growth Failure Through Time-specific Feeding Volume Increase

Chu, Sherman; White, Heather; Rindone, Shannon L; Tripp, Susan; Rhein, Lawrence

doi:10.1097/pq9.0000000000000366

Cited by 6 publications

(24 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The following factors such as: Stress, Autoimmune mechanisms, PROM, Inflammation, Bleeding, Uterine overdistension, Multiple pregnancies, disorders of axis (pituitary axis), Inflammation, Environmental factors, Social factors, Activation of mechanisms, induction of contractions leading to effacement and dilation of cervix and finally labor [51][52][53][54][55][56].…”

Section: Pathophysiology Of Preterm Labormentioning

confidence: 99%

“…Bacterial products and/or profibrous cytokines acting on cervical cells of the uterus may cause a change of MMPs expression. High concentrations MMP-8 of amniotic fluid are associated with PB (before the 32nd week of pregnancy) so induction of uterine contractions (directly or by functional "withdrawal" of progesterone) [50][51][52][53][54][55][56][57][58][59][60].…”

Section: Preterm Labor: the Mechanism Includesmentioning

confidence: 99%

“…Its allele gene A region −308 of the TNF-α promoter leads to an increase production of it. Roberts et al reported positive correlation between polymorphism of the TNF-α promoter region (−308 A allele) and the PB and/or premature rupture among African American women [50][51][52][53][54][55][56][57][58][59][60].…”

Section: Preterm Labor: the Mechanism Includesmentioning

confidence: 99%

“…The receptor antagonist of IL-1 inhibits the biological effects of IL-1, blocking its receptors. Consequently reduction of IL-1 production and induced from that of prostaglandin production by them endometrial tissue can prevent PB associated with infection Il-1β is found in chorionic villi, decidua, amniotic fluid and placental cultures [50][51][52][53][54][55][56][57][58][59][60]. Elevated levels of Il-6 are usually found in the amniotic fluid, with inflammation.…”

Section: Preterm Labor: the Mechanism Includesmentioning

confidence: 99%

“…The finding of extremelly high levels of the specific cytokine in the amniotic fluid pregnant women who presented with some kind of inflammation and its very low concentration in cases of PB "idiopathic" etiology, make it one of the most sensitive and specific PB indicators On the contrary, they were found to be reduced in cases of premature birth. Il-10 is also elevated in amniotic fluid after amniocentesis during the second trimester in pregnancies with IUGR and chorioamnionitis [50][51][52][53][54][55][56][57][58][59][60]. Interleukin-10 (IL-10) is known to be major inhibitory cytokine in the process synthesis of cytokines by both T cells (interferon-γ and IL-2), as well as by monocytes macrophages (TNF-α, IL-6, IL-8, and IL-12) and as therefore plays an important role in achieving the outcome of the pregnancy by securing the maternity tolerance to the allogeneic fetus.…”

Section: Preterm Labor: the Mechanism Includesmentioning

confidence: 99%

See 4 more Smart Citations

Premature Birth, Management, Complications

Tsikouras¹,

Bothou²,

Gerede³

et al. 2021

Global Women's Health

View full text Add to dashboard Cite

In recent years an increase in premature births (PB) rate has been noticed, as this pregnancy complication that still remain an important cause of perinatal morbidity and mortality, is multifactorial and prediction is not easy in many cases. There are many bibliographic data supporting the view that PB have also genetic predisposition. The trend of “recurrence” of PB in women as well as its increased frequency in ethnic groups suggests its association with genetic factors, either as such or as an interaction of genes and environment. Immunomodulatory molecules and receptors as well as polymorphisms of various genes and/or single nucleotides (single nucleotide polymorphisms, SNPs) now allow with advanced methods of Molecular Biology the identification of genes and proteins involved in the pathophysiology of PB. From the history of a pregnant woman, the main prognostic factor is a previous history of prematurity, while an ultrasound assessment of the cervix between 18 and 24 weeks is suggested, both in the developed and the developing world. According to the latest data, an effective method of successful prevention of premature birth has not been found. The main interventions suggested for the prevention of premature birth are the cervical cerclage, the use of cervical pessary, the use of progesterone orally, subcutaneously or transvaginally, and for treatment administration of tocolytic medication as an attempt to inhibit childbirth for at least 48 hours to make corticosteroids more effective. Despite the positive results in reducing mortality and morbidity of premature infants, the need for more research in the field of prevention, investigation of the genital code and the mechanism of initiation of preterm birth is important.

show abstract

Section: Pathophysiology Of Preterm Labormentioning

confidence: 99%

Section: Preterm Labor: the Mechanism Includesmentioning

confidence: 99%

Section: Preterm Labor: the Mechanism Includesmentioning

confidence: 99%

Section: Preterm Labor: the Mechanism Includesmentioning

confidence: 99%

Section: Preterm Labor: the Mechanism Includesmentioning

confidence: 99%

See 3 more Smart Citations

Premature Birth, Management, Complications

Tsikouras¹,

Bothou²,

Gerede³

et al. 2021

Global Women's Health

View full text Add to dashboard Cite

show abstract

Impact of a targeted volume‐increase nutrition guideline on growth and body mass index in premature infants: A retrospective review

Philip

Davenport

Mannan

et al. 2021

J Parenter Enteral Nutr

Self Cite

View full text Add to dashboard Cite

Background:The negative impact of disproportionate growth in premature infants is well documented, but optimal nutrition practices needed to prevent an unhealthy body mass index (BMI) remain unclear.Methods: An evidence-based, volume-increase guideline that advanced feeding volumes from 150-160 to 170-180 ml/kg/day between the postmenstrual age (PMA) of 31 0/7 and 34 0/7 weeks was implemented in October 2017 for infants born at ≤32 0/7 weeks' gestational age. Data were collected on 262 infants' weight and length at birth and at discharge for 20 months before and 21 months after guideline implementation, and retrospective analysis was conducted to determine disproportionate growth by comparing BMIs (in g/cm 2 ) at birth and at discharge. Changes in infants' body habitus were determined through bivariate analysis of weight and length z-scores from the Fenton growth curve.Results: Implementation of a targeted volume nutrition guideline resulted in fewer infants with growth failure, defined as weight <10th percentile (19.5% vs 11.2%; P = .06) at discharge. Infants who received treatment according to the targeted nutrition guideline had a statistically significant reduction in disproportionately low BMI (8.6% vs 2.5%; P = .0380) and an increase in disproportionately high BMIs (4.3% vs 12.3%; P = .025). There was minor change in the percentage of disproportionately large infants who received the guidelines from birth to discharge (11.5% vs 12.3%). Conclusions:A targeted volume-increase nutrition guideline may prevent growth failure, with some effects on disproportionate growth in preterm infants born at ≤32 0/7 weeks' gestational age. CLINICAL RELEVANCY STATEMENTPremature neonates often face challenges with adequate early nutrition; the lack of proper nutrition often leads to growth failure or disproportionate growth. Our retrospective chart review was intended © 2021 American Society for Parenteral and Enteral Nutrition to assess the effectiveness of a targeted volume-increase nutrition guideline in preventing growth failure and disproportionate growth at neonatal intensive care unit (NICU) discharge in preterm infants. The long-term goal of this research is to optimize nutrition support for premature infants in the NICU that may encourage long-term growth and neurodevelopmental outcomes later in life.

show abstract

Developing a Respiratory Quality Improvement Program to Prevent and Treat Bronchopulmonary Dysplasia in the Neonatal Intensive Care Unit

Sanlorenzo

Hatch

2023

Clinics in Perinatology

View full text Add to dashboard Cite

An Initiative to Reduce Preterm Infants Pre-discharge Growth Failure Through Time-specific Feeding Volume Increase

Cited by 6 publications

References 34 publications

Premature Birth, Management, Complications

Premature Birth, Management, Complications

Impact of a targeted volume‐increase nutrition guideline on growth and body mass index in premature infants: A retrospective review

Developing a Respiratory Quality Improvement Program to Prevent and Treat Bronchopulmonary Dysplasia in the Neonatal Intensive Care Unit

Contact Info

Product

Resources

About