“…To address the land-use transportation interaction issue, some works (Smith and Liebman 1978;Los 1979;Meng, Yang, and Wong 2000;Yim et al 2011;Li, Li, and Lam 2014) were conducted, but still did not capture the changing demand over time and gradual network upgrades. On the other hand, in the last 10 years, time-dependent frameworks (Szeto andLo 2005, 2008; • proposing a framework for the bi-objective road network design problem with land-use transportation interaction over time and health cost consideration; • proposing a general health cost function, which simultaneously captures the health impacts of traffic emissions, noise, and accidents, due to network improvement projects; • considering affected population when evaluating the health cost, and demonstrating its significance; • illustrating a paradox phenomenon that with the increasing amount of emissions, the emission induced health cost is decreasing; • developing an ABC algorithm to solve the bi-level problem, the algorithm and the model can be used as a decision-making tool of transportation projects for many cities; and • pointing out the existence of the health inequity issue.…”