2001
DOI: 10.1016/s0378-5173(01)00592-0
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An investigation of mucus/polymer rheological synergism using synthesised and characterised poly(acrylic acid)s

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Cited by 94 publications
(32 citation statements)
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“…The value for the pH was chosen to mimic the pH of the small intestine (Fallingborg, 1999). pH dependence was not of interest in this research although it is known to change the mucoadhesive properties of the alginate mainly due to dissociation of functional groups (Mikos & Peppas, 1986;Riley et al, 2001). In Fig.…”
Section: Afm Tip Activation With Mucin Macromoleculesmentioning
confidence: 99%
“…The value for the pH was chosen to mimic the pH of the small intestine (Fallingborg, 1999). pH dependence was not of interest in this research although it is known to change the mucoadhesive properties of the alginate mainly due to dissociation of functional groups (Mikos & Peppas, 1986;Riley et al, 2001). In Fig.…”
Section: Afm Tip Activation With Mucin Macromoleculesmentioning
confidence: 99%
“…G′ represents the energy stored from the application of deformation to the material that can be recovered and reflects the elastic-like component in the material. On the other hand, G″ represents the energy lost from the application of deformation and reflects the viscouslike component of the material [41]. All samples were measured in the angular frequency range of 0.628-20 rad·s .…”
Section: Polymer/substrate Interaction Evaluationmentioning
confidence: 99%
“…It is also a non-immunogenic, non-carcinogenic and mucoadhesive polymer, which makes it a suitable candidate for biomedical applications, such as wound management, tissue engineering and drug delivery vehicle [97][98][99][100][101]. CTS as well shows permeation enhancer properties, and it can improve the paracellular route of absorption, which is important for the transport of hydrophilic compounds such as therapeutic peptides and antisense oligonucleotides across the membrane [102][103][104].…”
Section: Chitosanmentioning
confidence: 99%