An investigation of the levels of vitamins A, D, and E in the serum of Chinese pregnant women

Chen, Yujuan; Li, Zhandong; Mao, Cuiying; Xu, Kang; Zhang, Shuhua

doi:10.1002/jcla.22176

Cited by 7 publications

(8 citation statements)

References 27 publications

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“…Our results provide evidence of the potential association between maternal vitamin D deficiency and placental inflammation. Vitamin D deficiency in pregnant and lactating women is highly prevalent in China, including the Shanghai municipalities [37,38]. Foreign guidelines have been recommended to define the cutoff point of serum 25(OH)D for evaluating vitamin D status during pregnancy [16,39].…”

Section: Discussionmentioning

confidence: 99%

Severe vitamin D deficiency in the first trimester is associated with placental inflammation in high-risk singleton pregnancy

et al. 2019

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Section: Discussionmentioning

confidence: 99%

Severe vitamin D deficiency in the first trimester is associated with placental inflammation in high-risk singleton pregnancy

et al. 2019

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“…VE and VD levels decreased with age increasing. There were some reasons: some pregnant women did not take enough VA, 17.05% of pregnant women had VAD [15], and VA was insufficient in their breast milk [1, 18]; small babies did not intake enough VA from their mothers' breast milk. It was also possible because small children grew quicker and consumed more VA, and they did not get enough vitamins from food, and the serum VA levels were lower during the first few years.…”

Section: Discussionmentioning

confidence: 99%

“…As previously reported [15], fasting blood samples were centrifuged at 1000 rpm, for 10 min after collecting, and then the sera were stored at -20°C till analysis. Before analyzing, the serum was kept at room temperature for 10min, and 100 μ L of serum was mixed with 100 μ L of acetonitrile with internal standard and then centrifuged at 10000 rpm for 10 min.…”

Section: Methodsmentioning

confidence: 99%

“…Then 100 uL hexane extract was dried by stream of nitrogen gas, and the residue materials were dissolved in 50 μ L methane and then analyzed by High Performance Liquid Chromatography (HPLC) or Liquid Chromatography-Mass Spectra (LC-MS). The method was validated as previously, in terms of lower limit of quantification, accuracy, precision, linearity, and extraction recovery [15].…”

Section: Methodsmentioning

confidence: 99%

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An Investigation of Vitamin Levels Status in the Serum of Children in China

Chen

Liu

Mao

et al. 2018

BioMed Research International

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This study was to investigate the vitamin levels in the serum of children in the Northeast of China and some factors associated with the vitamin levels. The sera were obtained from 2096 normal children aged 1 month to 12 years in the Northeast of China. Vitamins A and E were detected using their sera by HPLC, and the level of vitamin D was detected by LC-MS. The 20 overweight children were chosen from the 7-8 age range and took additional vitamins studies for extra 3 months. The data were analyzed by IBM SPSS Statistics 21. The average levels of vitamins A, D, and E in sera samples from the 2096 children were 0.2715mg/L (95%CI, 0.2715-0.2791mg/L), 26.2848μg/L (95%CI, 25.7900-26.7786μg/L), and 8.6137mg/L (95% CI, 8.5077-8.7198mg/L), respectively. The percentages of vitamins A, D, and E deficiency were 19.61%, 47.47%, and 0.62%, respectively. For 20 children from the VDD or VAD groups, after giving them more VA and VD for 3 months, the levels of VA and VD in the sera were increased significantly; however, the average BMI has barely changed. According to our finding, vitamin D deficiency was severe, vitamin A deficiency was common, and vitamin E was insufficient in the sera of children in the Northeast of China. The levels of vitamins A, D, and E were correlated with age and overweight.

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“…In the study of Iwakawa et al, researchers associate dietary intake and blood water-soluble vitamin level (vitamin B2, vitamin C, niacin, and folate) in patients with ulcerative colitis 2 . Chen and co-workers note the correlation of the level of fat-soluble vitamin in the serum of pregnant women or children in Northeast China with the age and the daily regional habits 3 , 4 .…”

Section: Introductionmentioning

confidence: 99%

Separation of some vitamins in reversed-phase thin-layer chromatography and pressurized planar electrochromatography with eluent containing surfactant

Polak

Pajurek

2021

Sci Rep

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The separation of some water- and fat-soluble vitamins via micellar systems of reversed-phase high-performance thin-layer chromatography (HPTLC) and pressurized planar electrochromatography (PPEC) was subjected to research. Hence, the influence of the mobile phase composition (surfactant and acetonitrile concentration, eluent buffer pH) on the migration distances and zone separation of some vitamins (thiamine, riboflavin, niacin, pyridoxine, cyanocobalamin, folic acid, ergocalciferol and α-tocopherol) was investigated. Our results indicated that the applied technique has an impact on the solute order. Comparing the system capacity of HPLC and PPEC (measured as height of the theoretical plate) for the mobile phase systems with and without surfactant shows differences, especially for fat-soluble vitamin. The variances and reproducibilities (% RDS) values of the vitamin are less in PPEC than in TLC. Moreover, the migration distances of water-soluble vitamins are longer than fat-soluble ones. Overall, eluent consisting of 50% acetonitrile, 18.75 mM SDS, the buffer of pH 6.99 via the PPEC technique was most appropriate for determining the investigated vitamins in the artificial mixture and the two commercially available vitamin combinations.

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An investigation of the levels of vitamins A, D, and E in the serum of Chinese pregnant women

Abstract: According to our finding, the levels of vitamin A, D, and E in the sera of pregnant women in northeastern China were affected by where they live and their age. Vitamin D deficiency was very serious, vitamin A deficiency was common, while vitamin E seems to be sufficient.

Cited by 7 publications

References 27 publications

Severe vitamin D deficiency in the first trimester is associated with placental inflammation in high-risk singleton pregnancy

Severe vitamin D deficiency in the first trimester is associated with placental inflammation in high-risk singleton pregnancy

An Investigation of Vitamin Levels Status in the Serum of Children in China

Separation of some vitamins in reversed-phase thin-layer chromatography and pressurized planar electrochromatography with eluent containing surfactant

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