Aiming at the issues of smooth transition from IPv4 to IPv6 and interoperability in technical coexistence period about campus network, discussing the technical characteristics of IPv6 protocol, GNS3 and OPNET simulator, combined with the status of weakness of IPv6 technology, lack of IPv6 technology planning and financial support for network upgrade in the vast majority of colleges, adopted the simulation methods to build a network model of IPv4 and IPv6 to achieve the technologies study such as topology design, network configuration and testing, network performance design and evaluation of IPv6 campus network under the low-cost conditions.