An Official American Thoracic Society Clinical Practice Guideline: Exercise-induced Bronchoconstriction

Parsons, Jonathan P.; Hallstrand, Teal S.; Mastronarde, John G.; Kaminsky, David A.; Rundell, Kenneth W.; Hull, James H.; Storms, William W.; Weiler, John M.; Cheek, Fern; Wilson, Kevin C.; Anderson, Sandra D.

doi:10.1164/rccm.201303-0437st

Cited by 527 publications

(777 citation statements)

References 139 publications

Supporting

Mentioning

697

Contrasting

Unclassified

Order By: Relevance

“…12 Before spirometry testing, all asthma medications, including short-acting bronchodilators and long-acting bronchodilators, were withheld for 8 and 24 h, respectively. At least 2 acceptable and repeatable FEV 1 maneuvers were performed at baseline before a treadmill exercise challenge.…”

Section: Study Protocolmentioning

confidence: 99%

Prevalence of Exercise-Induced Bronchoconstriction Measured by Standardized Testing in Healthy College Athletes

et al. 2016

View full text Add to dashboard Cite

BACKGROUND: Exercise-induced bronchoconstriction (EIB) can lead to long-term respiratory illness and even death. EIB prevalence rates are both high and variable in college athletes. Prevalence rates may be underestimated due to ineffective testing and screening. The purpose of this study was to investigate the prevalence of EIB in college athletes by a standardized EIB test that can be used on many college campuses. In addition, we assessed the usefulness of self-reporting EIB/asthma (1) history, (2) symptoms, and (3) respiratory medication obtained from a simple screening questionnaire for predicting an EIB-positive athlete. METHODS: A standardized EIB test and self-report questionnaire were administered to college athletes on 10 different sports teams. Information collected included pulmonary function (spirometry), expired gas analysis (maximal oxygen uptake), CO 2 production, minute ventilation, EIB/asthma history, current symptoms, and medication use. RESULTS: Results showed that 34 of 80 athletes (42.5%) were EIB-positive by standardized exercise testing. The majority (76.5 and 58.8%) of the 34 athletes who tested positive self-reported a negative history or no symptoms, respectively. Also, 79.4% of the athletes who tested positive for EIB reported not using a respiratory medication. There were no significant differences in a positive EIB test when assessing interactions for history (P ‫؍‬ .93), current symptoms (P ‫؍‬ .12), or respiratory medication use (P ‫؍‬ .66). CONCLUSIONS: A high proportion of college athletes tested positive for EIB when using a standardized test. Positive history, current symptoms of EIB/asthma, and respiratory medication use were not predictive of a positive test. Many EIB-positive athletes are not using a respiratory medication. More work is needed to develop an effective screening tool and improve education for EIB in college athletes.

show abstract

Section: Study Protocolmentioning

confidence: 99%

Prevalence of Exercise-Induced Bronchoconstriction Measured by Standardized Testing in Healthy College Athletes

et al. 2016

View full text Add to dashboard Cite

show abstract

“…WADA (World Anti-doping Agency) new list of allowed medications permits the use of albuterol and salmeterol since 2010 and formoterol since 2013 without clinical confirmation, requiring a notification only. Inhaled corticoids are also allowed [35].…”

Section: Discussionmentioning

confidence: 99%

“…The two patients that showed a fall in FEV1 of more than 20% from baseline had no respiratory complaints or reported any trouble in doing their training physical activities. Some sports organizations have established EIB screening programs for all of their internationally competitive athletes but this is far from being a consensus [35]. On the other hand, it is clear that individuals with exercise associated respiratory complaints and/or a clinical diagnosis of asthma that are engaged in competitive sportive activities should be evaluated for EIB [3,8,9,12,15,20,24,35].…”

Section: Discussionmentioning

confidence: 99%

Exercise-Induced Bronchospasm in Soccer Athletes Living in a Tropical Humid Region

Gomes¹,

Filho²,

Júnior³

et al. 2018

J Sports Med Dop Stud

View full text Add to dashboard Cite

show abstract

“…From a sports medicine perspective improved care may constitute better diagnosis, management and education amongst athletes. Regardless of whether salbutamol is on or of the WADA list of banned substances team medical oicers must follow best practice in the diagnosis of respiratory conditions such as EIB prior to providing inhalers for therapeutic use [20].…”

Section: Discussionmentioning

confidence: 99%

The Impact of Inhaled Salbutamol on Repeated Sprint Ability in Pre- Fatigued Soccer Players

J¹,

M²

2015

J Sports Med Doping Stud

View full text Add to dashboard Cite

John et al., J Sports Med Doping Stud 2015, 5:S2 http://dx.doi.org/10.4172/2161 Research Article Open Access AbstractObjectives: Investigate the ergogenic effect of inhaling up to 1600 µg of salbutamol on intermittent running performance in pre-fatigued soccer players. Methods:In a single blind randomised repeated measures design seven male and six female soccer players volunteered to participant. All participants were regularly playing competitive soccer and had no history of asthma. Following familiarisation sessions participants visited the exercise physiology laboratory on three occasions to complete an intermittent running protocol followed by twelve 17.5 m sprints. Prior to each trial participants inhaled either: placebo, 800 µg inhaled salbutamol (SAL800) or 1600 µg inhaled salbutamol (SAL1600). Following completion of the sprints a sample from the irst urine passed was analysed for salbutamol concentration. A repeated measures ANOVA was used to compare the mean sprint time, maximal sprint power, peak blood lactate post sprints and post sprint salbutamol urine concentration between conditions.Results: Mean sprint time, maximum power, maximum velocity, peak HR and peak blood lactate during the 17.5 m sprints were not signiicantly different between treatments in soccer players. There was no signiicant difference between male and female players in urine drug concentration following SAL800 (mean + SD; 201.47 + 294.47 ng.ml -1 vs. 180.2 + 102.15 ng.ml -1 ) or SAL1600 (739.24 + 549.21 ng.ml -1 vs. 879.58 + 633.14 ng.ml -1 ). Three players urine drug concentrations were above the WADA decision limit set at 1200 ng.ml -1 . Conclusions:Inhaling up to 1600 µg inhaled salbutamol did not signiicantly improve repeated sprint performance. However, inhalation of 1600 µg may result in a urine concentration above the current WADA upper limit and decision limit leading to a positive test. Athletes should ensure they use inhaled salbutamol at therapeutic doses to avoid the risk of breaching the WADA decision limit.

show abstract

An Official American Thoracic Society Clinical Practice Guideline: Exercise-induced Bronchoconstriction

Abstract: The recommendations in this Guideline reflect the currently available evidence. New clinical research data will necessitate a revision and update in the future.

Cited by 527 publications

References 139 publications

Prevalence of Exercise-Induced Bronchoconstriction Measured by Standardized Testing in Healthy College Athletes

Prevalence of Exercise-Induced Bronchoconstriction Measured by Standardized Testing in Healthy College Athletes

Exercise-Induced Bronchospasm in Soccer Athletes Living in a Tropical Humid Region

The Impact of Inhaled Salbutamol on Repeated Sprint Ability in Pre- Fatigued Soccer Players

Contact Info

Product

Resources

About