An optofluidic dye concentration detector based on the pulsed photoacoustic effect

Roy, Kaustav; Thomas, Anjali; Paul, Souradip; Ashok, Anuj; Shastri, Vijayendra; Kalyan, Kritank; Singh, Mayanglambam Suheshkumar; Pratap, Rudra

doi:10.1117/12.2582656

Cited by 10 publications

(4 citation statements)

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“…[4][5][6] Micromachined Ultrasound Transducers (MUTs) [7][8][9][10] are becoming more common as a replacement for conventional transducers. 11 There has been a recent trend in employing such devices to make low-cost ultra-portable photoacoustic imaging (PAI) systems that will be useful for point-of-care imaging applications and thus complement more conventional imaging technologies like positron emission tomography (PET) and magnetic resonance imaging (MRI) because of its unique and promising technical features − more specifically, not only to achieve higher spatial resolution (∼ 150µm) at the depth ∼ cm for recovery of various and complex tissue pathophysiological information (molecular ([Hb], [HbO 2 ], SO, and total Hb), physical (acoustic and mechanical properties), tissue anatomy or morphology, and micro-vasculature structures non-destructively and non-invasively but also to facilitate development of multi-modality imaging systems 12,13 − that are of utmost clinical importance and thus, significant scientific impact. [14][15][16] .…”

Section: Introductionmentioning

confidence: 99%

Image quality enhancement of PMUT-based photoacoustic imaging

Paramanick¹,

Roy²,

Samanta³

et al. 2023

Photons Plus Ultrasound: Imaging and Sensing 2023

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Photoacoustic imaging (PAI) is now a very promising imaging technique that provides image with sufficient depth, good resolution, and optical contrast. A conventional PAI system is relatively expensive and mechanically bulky. The study demonstrated that MEMS PMUT achieves miniaturized ultrasound (US) sensor element (either single element or an array of elements) with superior performance in terms of power consumption, flexibility, broader bandwidth, and sensitivity. This implies that these technologically novel qualities hold promise for the use of PMUT as an acoustic sensor in PAI systems in place of the conventional piezoelectric bulk element-based spherical ultrasound (US) transducer. We report our study on the design and development of MEMS PMUT−(central frequency ~ 1MHz) based PAM−that integrates MEMS technology and imaging technology (specifically, photoacoustic imaging (PAI)). In this work, we present a temporal integration of the signals over a certain number (~20) of pulsed light-induced PA waves against the conventional technique to acquire a single 1D PA signals/data corresponding to one individual optical pulse−induced PA waves. This means to say that the enhancement of imaging performance with the use of PMUT acoustic sensor is associated with a reduction of obtainable temporal resolution, i.e., a trade-off exists. With the applied temporal integration method SNR has been improved ~ 20dB. The preliminary study demonstrates that the integration of PMUT in PA imaging modality holds promise as a future (imaging) technology both for biological studies and their applications.

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Section: Introductionmentioning

confidence: 99%

Image quality enhancement of PMUT-based photoacoustic imaging

Paramanick¹,

Roy²,

Samanta³

et al. 2023

Photons Plus Ultrasound: Imaging and Sensing 2023

Self Cite

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“…For other detection methods of a solution, conductivity/spectrophotometry can be used to detect the concentration of sodium, potassium, magnesium, calcium, and chloride ions in artificial freshwater [ 21 ]. The pulse photoacoustic effect can be used to detect the content of methylene blue in dye [ 22 ]. Machine vision analysis can detect the content of target substances in complex mixtures [ 23 ].…”

Section: Introductionmentioning

confidence: 99%

Online Rapid Detection Method of Fertilizer Solution Information Based on Characteristic Frequency Response Features

Gao

Jing-yuan

et al. 2023

Sensors

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Online rapid detection of a fertilizer solution’s type and concentration is crucial for intelligent water and fertilizer machines to realize intellectual precision variable fertilization. In this paper, a cylindrical capacitance sensor was designed based on the dielectric properties of the fertilizer solution, and an online rapid detection method of fertilizer type and concentration was proposed based on the characteristic frequency response mode. Three fertilizer solutions, potassium chloride, calcium superphosphate, and urea, were used as test objects. Ten concentrations of each fertilizer solution in the 10~100 g/L range were taken as the test fertilizer solution. Then, under the action of a series of sine wave excitation signals from 1 kHz to 10 MHz, the sensor’s amplitude-frequency/phase-frequency response data were obtained. The detection strategy of ‘first type, then concentration’ was adopted to realize rapid online detection of fertilizer type and concentration. Experimental results indicated that the maximum relative error of the sensor stability test was 0.72%, and the maximum error of concentration detection was 7.26%. Thus, the intelligent water and fertilizer machine can give feedback on the information of a fertilizer solution in real-time during the process of precise variable fertilization, thus improving the intelligence of water and fertilizer machines.

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“…The growth of the lesion in the coagulated region was monitored using photoacoustic imaging. [13][14][15][16] The reconstructed PA images of the coagulated lesion area were generated using linear array and circular array-based transducer. [17][18][19][20][21][22][23] Both reconstructions are well-matched with the theoretically calculated lesion size.…”

Section: Introductionmentioning

confidence: 99%

Simulation of HIFU based lesion variation and its monitoring using photoacoustic imaging

Yadav¹,

Paul²,

KS³

et al. 2023

Photons Plus Ultrasound: Imaging and Sensing 2023

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In the past two decades, High-Intensity Focused Ultrasound (HIFU) has been actively investigated for inducing tissue ablation for tumours, healing arteries and even skin tightening for inducing facelifts. Being a non-contact and non-invasive procedure, HIFU is an attractive alternative over other procedures like radio-frequency ablations and microwave ablations as these are semi-invasive methods. Computer simulations in this domain can provide us with a fast-track way to test and deduce results virtually before conducting related experiments. In this study, we simulated the properties of bovine liver tissue virtually in a MATLAB-based k-Wave toolbox to track lesion variations with varying HIFU on-time and with a constant amount of heat deposition. Photoacoustic reconstructions were also carried out with a linear and circular array of transducers using the simple Delay-And-Sum (DAS) algorithm to access the real-time imaging capability of this technique for HIFU therapy. All the results obtained are discussed and validated. This study will, in general, aid in deciding the HIFU configuration and operational parameters with respect to the tissue type, lesion size, and lesion location within the tissue.

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An optofluidic dye concentration detector based on the pulsed photoacoustic effect

Cited by 10 publications

References 0 publications

Image quality enhancement of PMUT-based photoacoustic imaging

Image quality enhancement of PMUT-based photoacoustic imaging

Online Rapid Detection Method of Fertilizer Solution Information Based on Characteristic Frequency Response Features

Simulation of HIFU based lesion variation and its monitoring using photoacoustic imaging

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