An optofluidic light detector based on the photoacoustic effect

Rossetto, Nicola; Fortunati, Ilaria; Gellini, Cristina; Feis, Alessandro; Ferrante, Camilla

doi:10.1016/j.snb.2016.04.046

Cited by 3 publications

(2 citation statements)

References 34 publications

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“…In water, the Φ fl decreases significantly for 23 and slightly for 24 with values of 0.40 and 0.94, respectively . Due to their high quantum yields rhodamine‐based dyes are less amenable as PA contrast agents and, similar to 20 , are often used as reference fluorophores in PAI investigations . Fluorescein‐ and rhodamine‐based dyes have both been the subject of a fundamental PAS study to accurately determine their fluorescence emission quantum yields.…”

Section: Molecular Photoacoustic Contrast Agentsmentioning

confidence: 99%

Molecular Photoacoustic Contrast Agents: Design Principles & Applications

Borg

Rochford

2018

Photochem & Photobiology

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Photoacoustic imaging (PAI) is a rapidly growing field which offers high spatial resolution and high contrast for deep-tissue imaging in vivo. PAI is nonionizing and noninvasive and combines the optical resolution of fluorescence imaging with the spatial resolution of ultrasound imaging. In particular, the development of exogenous PA contrast agents has gained significant momentum of late with a vastly expanding complexity of dye materials under investigation ranging from small molecules to macromolecular proteins, polymeric and inorganic nanoparticles. The goal of this review is to survey the current state of the art in molecular photoacoustic contrast agents (MPACs) for applications in biomedical imaging. The fundamental design principles of MPACs are presented and a review of prior reports spanning from early-to-current literature is put forth.

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Section: Molecular Photoacoustic Contrast Agentsmentioning

confidence: 99%

Molecular Photoacoustic Contrast Agents: Design Principles & Applications

Borg

Rochford

2018

Photochem & Photobiology

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“…The advantages of the fluidic side such as -controlled diffusion of miscible fluids, the creation of smooth immiscible fluid interfaces, ability to work as an excellent transport medium and the advantages of the optical side such as the availability of highly sensitive optical sensing techniques, localization of light to spot at the sub-micron scales, ability to manipulate objects has proven to be fascinating enough to create state of the art devices such as fluid lenses 9 , optofluidic microscopes 10 , resonators 11 , tweezers 12 and much more. With the advent of pulsed/modulated light sources, the field has further evolved, acting on the fluid contained in the microfluidic channel, producing sound [13][14][15][16][17][18][19][20][21] . This phenomenon of making sound from any object by illuminating it with pulsating light is called photoacoustics, which has several applications in diverse fields 22,23 .…”

Section: Introductionmentioning

confidence: 99%

A PMUT based photoacoustic system as a microfluidic concentration detector

Roy

Shastri

Kumar

et al. 2022

Photons Plus Ultrasound: Imaging and Sensing 2022

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We report on the development of a novel piezo-MEMS based optofluidic platform to detect the concentration of various species dissolved in a fluid. This platform employs piezoelectric micromachined ultrasound transducers (PMUTs) to work as a photoacoustic receiver, receiving ultrasound from fluid targets present in microfluidic channels while illuminated with a nanosecond pulsed laser. We fabricate both the PMUTs and the microfluidic channels and subsequently use them for the experiment. We also show the capability of PMUTs as a general photoacoustic receiver and demonstrate its signal-to-noise characteristics (~31) and its wide fractional bandwidth (~73%).

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