An Outbreak of Acute Sarcoidosis with Arthropathy in Norfolk

Jawad, Ali; Hamour, A. A.; Wenley, W. G.; Scott, Dgi

doi:10.1093/rheumatology/28.2.178

Cited by 16 publications

(8 citation statements)

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“…In Greece, all 57 patients with asymptomatic bilateral hilar lymphadenopathy due to sarcoidosis who presented between 1980 and 1989 were diagnosed between December and June in each year [2]. An outbreak of six cases of acute sarcoid arthropathy in May was identified in Norfolk, UK [3]. Four of these cases had EN and all had bilateral hilar adenopathy.…”

Section: Discussionmentioning

confidence: 99%

Seasonal clustering of sarcoidosis presenting with erythema nodosum

Wilsher

1998

Eur Respir J

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Seasonal clustering of sarcoidosis presenting with erythema nodosum (EN) has previously been reported only in the northern hemisphere. Of 59 patients presenting to a single centre in New Zealand with a new diagnosis of sarcoidosis, 21 had EN and three more had acute arthralgia without EN. These patients were compared with the rest of the cohort. The patients with EN or arthralgia alone presented exclusively between April and December, with peak clustering in the spring months of August, September and October (p<0.001, Fisher's exact test). This cohort was more likely to have a stage I chest radiograph and to be female (p<0.05), but there were no other differences between the groups. This is the first report of seasonal clustering in the southern hemisphere suggesting a common environmental trigger in the aetiology of sarcoidosis.

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Section: Discussionmentioning

confidence: 99%

Seasonal clustering of sarcoidosis presenting with erythema nodosum

Wilsher

1998

Eur Respir J

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“…The prevalence of sarcoidosis among close contacts (with grade I and II contact) are similar to those obtained in a subsequent study in which chest radiographic screenJörgensen [3] Sharma et al [16] Sarcoidosis: Family Contact Study Respiration 1998;65:34-39 [17] seasonal May-August Stewart and Davidson [10] spatial 2 sister-employee-friend Edmondstone and Wilson [11] time-space husband-wife wife-husband-sister Hills et al [18] time-space 14 people: hospital staff-cohabitating people Maffre et al [19] seasonal May-June Badrinas et al [20] seasonal April-June Jawad et al [21] time-space 6 acute cases of 400,000 population during 1 month in Norfolk Kern et al [22] professional 3 firefighters ing of family contacts was performed [35]. The current study provides information on family aggregation in a larger pool of relatives than recorded in other publications.…”

Section: Discussionmentioning

confidence: 99%

Sarcoidosis: Family Contact Study

Fité

Alsina²,

Antó³

et al. 1998

Respiration

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Aim: To assess the familial aggregation in sarcoidosis in our environment. Methods: The medical centers of Catalonia (Spain) were approached to identify, retrospectively, patients diagnosed as sarcoidosis from 1986 to 1988. 245 sarcoidosis cases were recorded (annual incidence: 1.36/100,000 inhabitants). Finally, in 1990 a telephone questionnaire was administered to 188 sarcoidosis cases. Results: These cases reported 3,757 familial contacts, 5 of whom had confirmed sarcoidosis. The clinical presentation of familial sarcoidosis was similar to nonfamilial sarcoidosis, only Löfgren syndrome stood out. The prevalence of sarcoidosis among familial contacts was 1.33/1,000. Conclusions: The familial association is low and corresponds with the low annual incidence in our community.

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“…Sarcoidosis affects persons of all races gender and age. Numerous studies have reported peak months for the onset of sarcoidosis from both hemispheres, such as March–May in London, March–April in Athens, January–June in Finland, April–June in Barcelona, April–August in Japan and spring months in New Zealand 3–9 . The purpose of this study was to determine whether environmental factor(s) were influencing the aetiology of sarcoidosis.…”

Section: Introductionmentioning

confidence: 98%