An Ovarian Hilus-cell Tumor Associated with Endometrial Carcinoma: Report of a Case

Huang, Tsau-Yuen; Holaday, William J.

doi:10.1093/ajcp/54.1.147

Cited by 7 publications

(2 citation statements)

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“…It seems hard to ignore the probable role of oestrogens in this situation. Furthermore adenocarcinoma of the endometrium has been identified in six patients (Husslein 195 1 ;Dunnihoo et al 1966;Huang & Holaday 1970;Salm 1974;Mohamed et al 1978).…”

Section: Discussionmentioning

confidence: 99%

Hilus cell tumour of the ovary with an associated endometrial carcinoma, presenting with male pattern baldness and postmenopausal bleeding. Case report

Ross

1984

BJOG

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Section: Discussionmentioning

confidence: 99%

Hilus cell tumour of the ovary with an associated endometrial carcinoma, presenting with male pattern baldness and postmenopausal bleeding. Case report

Ross

1984

BJOG

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“…The presence of Reinke's crys talloids is pathognomonic of the hilus cells. Despite the manifestations of obvious androgen excess, as described earlier, the endometrium of patients with hilus tumours may show hyperplasia or adenocarcinoma [15,16]. These tumours have also been reported in association with poly cystic ovarian syndrome, with gonadal dysgenesis in Turner's syndrome, and with thyrotoxicosis.…”

Section: Discussionmentioning

confidence: 83%

Pure Leydig Cell Tumour (Hilus Cell) of the Ovary: A Rare Cause of Virilization after Menopause

Baiocchi

Manci

Angeletti³

et al. 1997

Gynecol Obstet Invest

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A 58-year-old postmenopausal woman with high plasma testosterone levels and virilization, as demonstrated by hirsutism and alopecia, is presented. Urinary 17-ketosteroids and 17-hydroxycorticosteroids as well as the computed axial tomography scan of the adrenal glands were normal. Although no pelvic mass was detected by sonography or pelvic examination, the patient was found to have small pure Leydig cell tumour of the left ovary. Following total abdominal hysterectomy and bilateral salpingo-oophorectomy, the patient had regression of the hirsutism, and the plasma testosterone dropped to normal level.

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Lipid cell tumor of the ovary: An ultrastructural study

Ishida

Okagaki

Tagatz

et al. 1977

Cancer

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An ovarian lipid cell tumor without Reinke's crystalloids in a woman with secondary amenorrhea, minimal hirsutism, and elevated 17-ketosteroid excretion was studied by light and electron microscopy. Tumor cells were found in small clumps or scattered singly within a collagenous matrix. The cytoplasm of the tumor cells contained abundant smooth endoplasmic reticula, numerous mitochondria with tubular cristae, lipid droplets, lysosomal dense bodies, and concentric membranous whorls, characteristic of steroidogenic cells. In addition, "peripheral canalicular systems'' were found at the outer margins of the nests of the tumor cells. These "peripheral canalicular systems" were bordered by the cell membranes and the surrounding collagenous stroma into which microvilli projected. Since the intercellular canalicular system present between the tumor cells was continuous with the "peripheral canalicular system," both systems probably have a common function related to steroid metabolism. The intercellular and "peripheral" canalicular systems and cytoplasmic microfilaments found in this tumor suggest that this ovarian lipid cell tumor was derived from the ovarian stroma.

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An Ovarian Hilus-cell Tumor Associated with Endometrial Carcinoma: Report of a Case

Cited by 7 publications

References 0 publications

Hilus cell tumour of the ovary with an associated endometrial carcinoma, presenting with male pattern baldness and postmenopausal bleeding. Case report

Hilus cell tumour of the ovary with an associated endometrial carcinoma, presenting with male pattern baldness and postmenopausal bleeding. Case report

Pure Leydig Cell Tumour (Hilus Cell) of the Ovary: A Rare Cause of Virilization after Menopause

Lipid cell tumor of the ovary: An ultrastructural study

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