An Overview of Phytotherapy Used in the Management of Type II Diabetes

Abstract

: Diabetes mellitus is related to unconstrained high blood sugar, and it is linked with long-term impairment, dysfunction, and failure of several organs. Since 1980, the global frequency of diabetes has almost doubled in the adult population. In very rare cases of poor prevention and management programs, diabetes will cause the deteriorated effects on the health and lifespan of the world population, and so on the world economy. Supplements, however, help in the improvement of nutritional deficiencies. Phytotherapeutics has the advantage of being low in cost and easy to access with marginal side effects. So, these are preferred candidates to be used as potential treatment approaches in the management of diabetes. Currently, a multitude of pharmaceuticals is used that is derived from natural compounds having medicinal properties. The mechanistic approach involves regulation of insulin signaling pathways, translocation of GLUT-4 receptors and/or activation of PPAR γ. These natural compounds include numerous flavonoids which help in preventing glucose absorption by preventing the absorption of α-amylase and α-glucosidase. However, to authenticate the efficacy and safety profile of these compounds, detailed validatory clinical studies are required. This review majorly focuses on the mechanistic approaches of various naturally derived compounds relevant in the condition of Diabetes mellitus.

APLICABILIDADE DA FITOTERAPIA NO TRATAMENTO DE INFECÇÕES ORAIS CAUSADAS POR Escherichia coli E Enterococcus faecalis

“…Na Odontologia, a valorização, aceitação e a aplicação da fitoterapia têm sido perceptíveis, uma vez que esta ciência tem demonstrado resultados promissores, apresenta baixo custo, fácil acessibilidade, biocompatibilidade e menor probabilidade de causar efeitos colaterais (Enioutina et al, 2017;Jahangir et al, 2020;Sharma et al, 2021). avaliaram por seis meses a ação de um medicamento à base de plantas medicinais, obtendo eficácia em várias lesões, além de observarem redução da intensidade dolorosa e da taxa de ocorrência em comparação ao grupo controle.…”

α-Pinene, a Main Component of Pinus Essential Oils, Enhances the Expression of Insulin-Sensitive Glucose Transporter Type 4 in Murine Skeletal Muscle Cells

“…It has been demonstrated that a range of medicinal plants and fruit-and vegetablebased foods can intervene at critical stages of glucose metabolism and could potentially be used to develop new anti-diabetic medications [9,10]. There are multiple mechanisms underlying their anti-diabetic effects, including intervening with the insulin receptor signaling pathways, the translocation of GLUT4 receptors, the activation of PPAR-γ, or the reduction of intestinal glucose absorption [11]. For centuries, essential oils (EOs) have been employed for medicinal and traditional practices.…”

Os benefícios da fitoterapia na Odontologia

“…Uma abordagem interessante é explorar as inúmeras propriedades das plantas medicinais. A valorização, aceitação e o emprego da fitoterapia na odontologia tem sido notório pois apresenta baixo custo, fácil acesso, biocompatibilidade e principalmente tem apresentado resultados promissores (Enioutina et al, 2017;Jahangir et al, 2020;Sharma et al, 2021).…”