An overview of the current progress, challenges, and prospects of human biomonitoring and exposome studies

Bocato, Mariana Zuccherato; Ximenez, João Paulo Bianchi; Hoffmann, Christian; Barbosa, Fernando

doi:10.1080/10937404.2019.1661588

Cited by 68 publications

(45 citation statements)

References 227 publications

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“…Hair is a non-invasive matrix, easy to store and transport, and its main advantage is a wide time window for exposure assessment [14] [15]. While hair mineral analysis is an attractive biomarker of exposure to toxic elements, there are more questions than answers regarding the validity of this method in diagnostics of elemental status [16]. There are still controversies regarding the use of hair mineral analysis as a diagnostic method.…”

Section: Teethmentioning

confidence: 99%

Hair Trace Elements in Children With Autism Spectrum Disorders: Systematic Literature Review

Mikulewicz

Chojnacka

2021

Preprint

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(1) Background: The aim of this work was to systematically review the literature on the relation between the levels of elements in hair (toxic elements and trace elements) on the occurrence of autism spectrum disorder. (2) Methods: Search strategy and study selection: Original articles were included if they met the including criteria that report the trace element levels in hair. The following databases were screened: Medline (via PubMed), Scopus, Web of Science, Google Scholar (from 2000.01.01 to 2020.11.11). The main search terms used were “hair element analysis and trace elements and autism”. (3) Results: The papers available describe results of studies undertaken with the use of different methodology: diversified size of experimental groups, different sampling and analytical techniques. Therefore direct comparison of the results is not informative. (4) Conclusions: It was found that pathogenesis of autism spectrum disorder was associated with the exposure to toxic elements (e.g. Hg and Pb) which act as neurotoxicants. Also, the relation between some microelements seem to be significant, in particular the ratio Zn/Cu. Higher level of zinc and level levels of copper play the protectory role.

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Section: Teethmentioning

confidence: 99%

Hair Trace Elements in Children With Autism Spectrum Disorders: Systematic Literature Review

Mikulewicz

Chojnacka

2021

Preprint

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“…Cancer management and prevention provide examples [ 38 ] of important current applications for the use of big data analytics. One example is the combination of data from multiple sources (e.g., DNA germ line and tumor sequencing, gene expression, epigenetics, proteomics) along with clinical patient information and environmental exposures [ 39 ] to determine individualized cancer therapeutic strategies. A specific application of machine learning analytics is in breast cancer screening.…”

Section: Data Science: Machine Learning Predictive Analytics and Hementioning

confidence: 99%

The intersection of genomics and big data with public health: Opportunities for precision public health

et al. 2020

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“…On the other hand, despite extensive study and public discussion of the adverse effects of environmental contaminants, there still no strong experimental evidence for it. This opinion is based mainly on the indirect indicesassociation between health disorders rate and occupational exposition of the limited number of people to environmental contaminants (Sirotkin and Harrath 2017;Tarko et al 2020;Tenailleau et al 2020) or presence of these contaminants in tissues (Bocato et al 2019). The available data concerning the association between exposure to contaminants and objective physiological parameters are few, contradictory and usually inconclusive (Louzen et al 2019).…”

Section: Mythic Interconnectionmentioning

confidence: 99%

Untitled

2020

REJHSS

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The cross-cutting theme of the 3/2 issue of Researcher is the problem of transformation of human nature in civilizational, historical, and cultural dimensions. The opening essay by Ilia Delio focuses on the current semantic context of this transformation and its cons equences, which change taken for granted values in daily life. The author announces the end of an era that affirms the value of an autonomous liberal subject, and connects the future with the beginning of the history of post-human being, a new type of personality integrated into the "maps of connections" (through socialism, pol itics, environment, economics, sexuality, etc.). Arkady Ursul develops the topic of information transformation, which shows that essence of globalization is the approval of the tr iad of universals: spatial distribution, integration and universality. Through the prism of these universals, the author considers cultu ral genesis and predicts the "global developmental algorithms" of man in the information world. Konstantin Kolin analyzes the main challenges of modern civil ization that should be overcome in the process of globalist discourse of civilizational transformation. The author includes the geopolit ical concept of "nuclear deterrence", the ideology of post-industrial society, the exhaustion of natural resources, and the development of artificial intelligence to these challenges. The answer to these challenges should be a new enlightenment in which the focus is on caring for the future of the planet, and on finding a balance in sol ving global problems. An essay by Italian researcher of Russian history, Ornella Calvarese, is dedicated to the wandering bards of ancient Russiakaliki. Turning to the study of a Russian Middle Ages phenomenon, the author draws a conclusion about the cultural role of spiritual nomadism, which has influenced and still continues to influence the Russian worldview. A deep historical perspective allows us to recreate the past, reveal hidden meanings, restore national identity against the background of spasmodic, often interrupted stages of transformation of Russian culture. We continue to publish Nadezhda Gonotskaya's research piece "Recipe: the Apotheosis of Rationality or the Magic of Life?". In this second part of her essay, attention is paid to a special case of

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An overview of the current progress, challenges, and prospects of human biomonitoring and exposome studies

Cited by 68 publications

References 227 publications

Hair Trace Elements in Children With Autism Spectrum Disorders: Systematic Literature Review

Hair Trace Elements in Children With Autism Spectrum Disorders: Systematic Literature Review

The intersection of genomics and big data with public health: Opportunities for precision public health

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