An ultra-high pressure liquid chromatography-tandem mass spectrometry method for the quantification of teicoplanin in plasma of neonates

Begou, Olga; Kontou, Aggeliki; Raikos, Νikolaos; Sarafidis, Kosmas; Roilides, Emmanuel; Papadoyannis, Ioannis N.; Gika, Helen

doi:10.1016/j.jchromb.2016.01.042

Cited by 21 publications

(27 citation statements)

References 24 publications

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“…The highest recovery (more than 80%) was reached using ice-cold acetonitrile in a 3/1 (v/v) ratio. All other investigated combinations gave lower recoveries (Begou et al, 2017). Also, trichloroacetic acid can be applied as a precipitation agent for extraction of vancomycin in plasma or serum (Sheng & Zhou, 2017;Bijleveld et al, 2014, Brozmanová et al, 2017.…”

Section: Methodsmentioning

confidence: 97%

“…Protein precipitation was the method of choice for preparation of samples containing vancomycin or teicoplanin (Javorska et al, 2017;Begou et al, 2017;Sheng & Zhou, 2017;Brozmanová et al, 2017;Wicha & Kloft, 2016;Oyaert et al, 2015;Cao et al, 2014;Zhang et al, 2014b;Bijleveld et al, 2014;Cazorla-Reyes et al, 2014). Acetonitrile is frequently used as a precipitation agent for preparing plasma, serum, urine or peritoneal/pleural effusion containing vancomycin, and plasma or serum containing teicoplanin, giving a good extract purity (Oyaert et al, 2015;Cao et al, 2014, Javorska et al, 2017Cazorla-Reyes et al, 2014, Begou et al, 2017Cazorla-Reyes et al, 2014). However, acetonitrile did not achieve sufficient recovery for vancomycin determination in plasma or serum (Cao et al, 2014;Cazorla-Reyes et al, 2014).…”

Section: Methodsmentioning

confidence: 99%

“…For determination of vancomycin and teicoplanin, isocratic or gradient elution modes have been applied (Zhang et al, 2014a, Javorska et al, 2017Begou et al, 2017;Sheng & Zhou, 2017;Brozmanová et al, 2017;Kim et al, 2016;Wicha & Kloft, 2016;Oyaert et al, 2015;Cao et al, 2014;Zhang et al, 2014b;Bijleveld et al, 2014;Li et al, 2014;Cazorla-Reyes et al, 2014). In isocratic mode, phosphate buffer was mixed with acetonitrile for the analysis of vancomycin, and analysis time was 10 min (Zhang et al, 2014a).…”

Section: Liquid-liquid Extraction (Llq)mentioning

confidence: 99%

“…The most frequently used organic solvent in gradient mode for quantitative determination of vancomycin and/ or teicoplanin is acetonitrile, but some authors reported use of methanol for analysis of these two drugs (Javorska et al, 2017;Begou et al, 2017;Sheng & Zhou, 2017;Brozmanová et al;Kim et al, 2016;Wicha & Kloft, 2016;Oyaert et al, 2015;Cao et al, 2014;Bijleveld et al, 2014;Li et al, 2014;Zhang, 2014aZhang et al, 2014bCazorla-Reyes et al, 2014). In most cases, the aqueous phase consisted of water with different contents of formic acid (0.01-0.1%) (Javorska et al, 2017;Begou et al, 2017;Kim et al, 2016;Wicha & Kloft, 2016;Oyaert et al, 2015;Cazorla-Reyes et al, 2014;Zhang et al, 2014a;Zhang et al, 2014b;Li et al, 2014;). Also, it was reported that the aqueous phase could contain phosphate and ammonium acetate buffer (Cao et al, 2014;Sheng & Zhou, 2017;Brozmanová et al, 2017;Bijleveld et al, 2014;.…”

Section: Liquid-liquid Extraction (Llq)mentioning

confidence: 99%

“…Matrix components influence the ionization efficiency in the ionization source, reducing the sensitivity of the method. Techniques commonly used for sample preparation include protein precipitation (PP), liquid-liquid extraction (LLE) solid-phase extraction (SPE), and in this review their application for sample treatment for the two glycopeptide antibiotics is presented (Javorska et al, 2017;Begou et al, 2017;Kim et al, 2016;Sheng & Zhou, 2017;Brozmanová et al, 2017;Wicha & Kloft, 2016;Oyaert et al, 2015;Cao et al, 2014;Cazorla-Reyes et al, 2014;Zhang, 2014a;Zhang et al, 2014b;Bijleveld et al, 2014;Li et al, 2014).…”

Section: Introductionmentioning

confidence: 99%

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Overview of the analytical methods for vancomycin and/or teicoplanin determination in biological matrices

Stajić

Jančić–Stojanović

2017

VET GLASNIK

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Background. Teicoplanin and vancomycin are glycopeptide antibiotics currently in use for treatment of multidrug-resistant bacterial infections. Scope and Approach. Severe undesirable effects, such as ototoxicity, nephrotoxicity and neutropenia have been reported for vancomycin and teicoplanin, which necessitates monitoring the concentration of these two drugs in different biological samples. In order to obtain precise and accurate results, sensitive, reliable and fast methods are necessary. The main aim of this mini review is to give a clear and concise overview of the recently developed, validated, novel and improved methods for glycopeptide antibiotic analyses in various biological matrices. Also, the variability of the matrices requires optimal and effective sample preparation procedures to be developed, and so these are discussed. Key Findings and Conclusions. Different liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods have been described for quantitative determination of glycopeptide antibiotics in various biological matrices. It was shown that protein precipitation was a convenient method for sample preparation despite the high number of novel sample preparation methods.

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Section: Methodsmentioning

confidence: 97%

Section: Methodsmentioning

confidence: 99%

Section: Liquid-liquid Extraction (Llq)mentioning

confidence: 99%

Section: Liquid-liquid Extraction (Llq)mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Overview of the analytical methods for vancomycin and/or teicoplanin determination in biological matrices

Stajić

Jančić–Stojanović

2017

VET GLASNIK

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A novel sensitive analytical method for the simultaneous analysis of vancomycin and teicoplanin in human urine via single high‐performance liquid chromatography coupled with photodiode array and mass spectrometry in series

Giakoumaki

Sarigiannis

Hapeshi

2022

J of Separation Science

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Analysis of vancomycin and teicoplanin in biological fluids is vital since they are used in the treatment of hospital infections. For the determination of both glycopeptides in urine, a sensitive and accurate analytical method using high‐performance liquid chromatography coupled with photodiode array and mass spectrometry was developed and validated. This research work is the first attempt to develop a chromatographic method for the determination of two glycopeptides with structural similarities. Moreover, the used non‐invasive sampling method is an advantage of this research effort, especially when the blood sampling is difficult. Urine was treated with acetonitrile and 5% trichloroacetic acid, followed by solid‐phase extraction. The chromatographic separation was established at a C18 column (4.6 × 150 mm, 5 μm), using a gradient method and an electrospray ionization source in a positive mode. The linearity of the method was R2≥ 0.9900. The precision was estimated with a maximum coefficient of variation below 15%, while the accuracy ranged from 64 to 121%. The limit of detection and quantification of both glycopeptides ranged from 0.076 up to 0.33 mg/L and 0.33 up to 2.1 mg/L, respectively, showing the same sensitivity as the triple quadrupole mass spectrometry, which is the most frequently used method.

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Recent Trends in Therapeutic Drug Monitoring of Peptide Antibiotics

Kilianova,

Cizmarova,

Spaglova

et al. 2024

J of Separation Science

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Antimicrobial peptides take a specific position in the field of antibiotics (ATBs), however, from a large number of available molecules only a few of them were approved and are used in clinics. These therapeutic modalities play a crucial role in the management of diseases caused by multidrug‐resistant bacterial pathogens and represent the last‐line therapy for bacterial infections. Therefore, there is a demand for a rationale use of such ATBs based on optimization of the dosing strategy to minimize the risk of resistance and ensure the sustainable efficacy of the drug in real clinical practice. Therapeutic drug monitoring, as a measurement of drug concentration in the body fluids or tissues, results in the optimization of the patient´s medication and therapy outcome. This strategy is beneficial and could result in tailored therapy for different types of infection and the prolongation of the use and efficacy of ATBs in hospitals. This review paper provides an actual overview of approved antimicrobial peptides used in clinical practice and covers current trends in their analysis by convenient and advanced methodologies used for their identification and/or quantitation in biological matrices for therapeutic drug monitoring purposes. Special emphasis is given to the methods with perspective clinical outcomes.

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An ultra-high pressure liquid chromatography-tandem mass spectrometry method for the quantification of teicoplanin in plasma of neonates

Cited by 21 publications

References 24 publications

Overview of the analytical methods for vancomycin and/or teicoplanin determination in biological matrices

Overview of the analytical methods for vancomycin and/or teicoplanin determination in biological matrices

A novel sensitive analytical method for the simultaneous analysis of vancomycin and teicoplanin in human urine via single high‐performance liquid chromatography coupled with photodiode array and mass spectrometry in series

Recent Trends in Therapeutic Drug Monitoring of Peptide Antibiotics

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