An Uncommon Cause of Hematochezia

Ishtiaq, Rizwan; Aziz, Muhammad; Wilhelm, Darlene M.; Gaduputi, Vinaya; Hamdani, Syed Uzair

doi:10.1007/s12029-020-00470-4

Cited by 1 publication

(1 citation statement)

References 15 publications

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“…We found a total of 21 case reports of pancreatic cancer presenting as GIB in the past 20 years (Table 1). [1,[4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23] By summarizing the literature, we think pancreatic cancer presenting as GIB has several mechanisms: 1. The tumor directly Higashiyama et al [17] 69/- invades gastrointestinal tract, such as the stomach, duodenum, and colon; 2.…”

Section: Discussionmentioning

confidence: 99%

Pancreatic head cancer with gastrointestinal bleeding as the initial manifestation: a case report and literature review

Zheng

Niu

et al. 2023

Journal of Pancreatology

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Gastrointestinal bleeding (GIB) as the initial symptom is rare in patients with pancreatic cancer, which is prone to misdiagnosis and should be paid attention to by clinicians. Here, we present a patient with pancreatic head cancer whose first symptom was only severe upper gastrointestinal bleeding, which initially led to misdiagnosis. However, subsequent imaging revealed a mass in the pancreatic head which was considered a malignant tumor. After surgical resection, the pathology confirmed that the mass in the pancreatic head was pancreatic ductal adenocarcinoma, and the duodenal bulb’s full thickness was infiltrated. A literature review found that pancreatic cancer can present gastrointestinal bleeding by invading the digestive tract and blood vessels, left-sided portal hypertension (LSPH), digestive tract metastasis, and canceration of ectopic pancreatic tissue in the digestive tract. For these cases, clinicians should utilize multidisciplinary diagnosis and treatment based on digestive endoscopy, imaging, interventional therapy, and surgery to control bleeding, identify etiology, and remove tumors.

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