2015
DOI: 10.1111/pai.12361
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An unusual case of penile non‐pigmenting fixed drug eruption in a child

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Cited by 8 publications
(5 citation statements)
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“…NPFDE is a very rare variant that is characterized by the absence of residual hyperpigmentation. Few cases have been reported in adults [2], and only 2 cases have been reported in children [5,6]. We report a case of NPFDE with skin desquamation and onycholysis induced by amoxicillin, as confirmed with a DCT.…”
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confidence: 79%
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“…NPFDE is a very rare variant that is characterized by the absence of residual hyperpigmentation. Few cases have been reported in adults [2], and only 2 cases have been reported in children [5,6]. We report a case of NPFDE with skin desquamation and onycholysis induced by amoxicillin, as confirmed with a DCT.…”
mentioning
confidence: 79%
“…NPFDE is a rare delayed drug reaction. Only 2 cases have been reported in children: a 13-year-old with NPFDE in the form of bullous desquamation on the palms and soles induced by amoxicillin and rifamycin [5] and a 10-year-old boy with NPFDE in the form of penis swelling induced by amoxicillin [6]. To our knowledge, there have been no reported cases of desquamative NPFDE induced by amoxicillin, as demonstrated by DCT, in a boy.…”
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confidence: 96%
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“…9 More recently, an atypical penile non-pigmenting FDE to amoxicillin has been diagnosed in a 10-year-old boy. 10 Clinical Implications: We report the first case of classical fixed drug eruption selective to amoxicillin in the pediatric setting. Our case highlights the importance of drug provocation test in diagnosing this entity and that cross-reactivity to similar molecules might be absent.…”
Section: A Pediatric Case Of Selective Fixed Drug Eruption To Amoxicimentioning
confidence: 98%
“…Indeed, the only other case in the pediatric literature that assessed tolerability to other betalactams performed challenges with penicillin V and cefuroxime, a third-generation cephalosporin that does not share its lateral chain with amoxicillin. 10 Therefore, it appears that none of the amoxicillin- The condition is a result from structural defects in the brain and spinal cord, leading to impaired cerebrospinal fluid. 1 Most cases of Chiari malformations occur during fetal development while much less commonly, they can occur later in life.…”
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confidence: 99%