An Unusual Manifestation of Herpes Simplex Virus–Associated Acute Iris Depigmentation and Pigmentary Glaucoma

Dastrup, B. Travis; Cantor, Louis B.; Moorthy, Ramana S.; Vasconcelos-Santos, Daniel Vítor; Rao, Narsing A.

doi:10.1001/archophthalmol.2010.364

Cited by 10 publications

(9 citation statements)

References 5 publications

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“…For example, it was found in the corneoscleral specimen of an eye with acute iris depigmentation and elevated IOP [34]. The clinical features of this patient are similar to those seen in a series of 28 eyes with bilateral acute depigmentation of the iris [35], in which PCR analysis of the aqueous was performed in two eyes and was negative for all the three herpes viruses.…”

Section: Introductionsupporting

confidence: 67%

Viral anterior uveitis

Jap¹,

Chee²

2011

Current Opinion in Ophthalmology

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Section: Introductionsupporting

confidence: 67%

Viral anterior uveitis

Jap¹,

Chee²

2011

Current Opinion in Ophthalmology

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“…Rarely, HSV has been reported to cause Posner-Schlossman syndrome, Fuchs uveitis syndrome, or acute iris depigmentation and pigmentary glaucoma [12][13][14] . The inflammation becomes chronic with persistently raised IOP unless specific antiviral therapy is instituted.…”

Section: Discussionmentioning

confidence: 99%

Herpetic uveitis: The masquerader

Kausar¹

2022

Int. J. Med. Ophthalmol.

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Although a large proportion of anterior uveitis is noninfectious, viruses are regarded as an important cause of infectious anterior uveitis. Herpes viruses are common infectious causes of hypertensive anterior uveitis. PCR analysis of aqueous sample collected at the slit lamp under aseptic conditions for viral DNA is commonly used technique to confirm the diagnosis during the acute phase. Anterior uveitis may be shortened by the prompt use of therapeutic doses of antiviral therapy and maintenance therapy may be effective in decreasing disease recurrence. In eyes with raised IOP, topical antiglaucoma medications can be given. Eyes with severe elevation of IOP may require oral carbonic anhydrase inhibitors, and filtration surgery may be indicated in medically uncontrolled glaucoma with optic neuropathy. Abbreviations: herpes simplex virus (HSV), varicella-zoster virus (VZV), cytomegalovirus (CMV), intraocular pressure (IOP), Keratic precipitates (KPs).

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“…Diffuse iris atrophy is uncommon (10% of eyes) [8]. Rarely, HSV has been reported to cause Posner-Schlossman syndrome, Fuchs uveitis syndrome, or acute iris depigmentation and pigmentary glaucoma [12][13][14]. The inflammation becomes chronic with persistently raised IOP unless specific antiviral therapy is instituted.…”

Section: Discussionmentioning

confidence: 99%

Herpetic Uveitis – The Masquerader

Kausar¹

2020

WJOVR

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An Unusual Manifestation of Herpes Simplex Virus–Associated Acute Iris Depigmentation and Pigmentary Glaucoma

Cited by 10 publications

References 5 publications

Viral anterior uveitis

Viral anterior uveitis

Herpetic uveitis: The masquerader

Herpetic Uveitis – The Masquerader

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