An Unusual Variant of Cutaneous Sarcoidosis

Abstract

Sarcoidosis is a multisystem inflammatory disease of unknown etiology, characterized by noncaseating granuloma variably infiltrating the respiratory tract, ganglions, eyes, internal organs and the skin. The heterogeneity of cutaneous sarcoidosis represents a diagnostic challenge for physicians and affirms its reputation as a "great imitator". Common specific lesions associated with sarcoidosis are papules, plaques, nodules, scar sarcoidosis and lupus pernio. Atypical presentations of sarcoidosis do exist and include ichthyosiform, alopecic, erythrodermic, angiolupoid and verrucous variants. Verrucous sarcoidosis is an extremely rare manifestation. Previous reports of this phenotype are limited to 16 cases, with only 5 previous reports of facial verrucous sarcoidosis reported in the literature. Here we report a case of a 50-year-old Moroccan woman who had an unusual cutaneous presentation of facial verrucous sarcoidosis. IMAGE ARTICLE Check for updates Discussion Variability in the cutaneous features of sarcoidosis affirms the condition's designation as one of dermatology's "great imitators" [2]. The diagnosis often requires a clinical presentation congruent with histologic features in addition to exclusion of confounding aetiologies [3]. Verrucous sarcoidosis (VS) is an extremely rare subtype [4], with only 16 cases previously reported [5]. It was first